Center for Community-Based Healthcare Research and Education (CoHRE), Head Office for Research and Academic Information, Shimane University, Izumo, Shimane, Japan.
Center for Primary Health Care Research, Lund University, Malmö, Sweden.
Scand J Med Sci Sports. 2023 Aug;33(8):1552-1559. doi: 10.1111/sms.14386. Epub 2023 May 11.
This longitudinal study examined the relationship between flexibility-activity and blood-pressure (BP) change among older adults in Japan. Our study included 452 older adults who took part in our survey in both 2012/2013 and 2017/2018. The seated systolic blood pressure (SBP) and diastolic BP (DBP) were measured both at baseline and at the 5 years follow-up. The frequencies of the different physical activities at baseline were assessed using a questionnaire. A generalized linear mixed model was used to estimate the non-standardized coefficient (B) of BP change associated with flexibility activity, after adjustments for sex, age, body mass index, smoking status, alcohol consumption, antihypertensive medication use, history of heart disease, walking time, and muscle-strengthening activity as a fixed-effect, and area of residence as a random-effect. Higher flexibility-activity frequency was significantly associated with reduced SBP (B = -0.77 [95% confidence intervals = -1.36, -0.18], p for linear trend = 0.01, p for quadratic trend = 0.85) and DBP (-0.33 [-0.71, 0.05], p for linear trend = 0.09, p for quadratic trend = 0.04). Engaging in flexibility activity for 3 days per week was significantly associated with a reduction in DBP (B = -4.16, 95% CI [-7.53, -0.79], p = 0.02) compared with that in the reference group (0 days per week). Interaction tests were not significant between basic variables (sex, age, BMI, and antihypertensive medication) and flexibility. In conclusion, higher flexibility activity frequency was associated with a reduction in BP in older adults. Future longitudinal and interventional studies should examine the effects of flexibility activity on cardiovascular disease prevention.
本纵向研究考察了日本老年人柔韧性-活动与血压（BP）变化之间的关系。我们的研究纳入了 452 名在 2012/2013 年和 2017/2018 年参加我们调查的老年人。在基线和 5 年随访时测量了坐位收缩压（SBP）和舒张压（DBP）。基线时使用问卷评估了不同身体活动的频率。采用广义线性混合模型，在调整性别、年龄、体重指数、吸烟状况、饮酒状况、使用抗高血压药物、心脏病史、步行时间和肌肉强化活动等固定因素后，估计与柔韧性活动相关的 BP 变化的非标准化系数（B），并将居住地作为随机因素。较高的柔韧性活动频率与 SBP 降低显著相关（B=-0.77[95%置信区间=-1.36，-0.18]，线性趋势 p=0.01，二次趋势 p=0.85）和 DBP 降低（B=-0.33[-0.71，0.05]，线性趋势 p=0.09，二次趋势 p=0.04）。与参考组（每周 0 天）相比，每周进行 3 天柔韧性活动与 DBP 降低显著相关（B=-4.16，95%CI[-7.53，-0.79]，p=0.02）。基本变量（性别、年龄、BMI 和抗高血压药物）与柔韧性之间的交互检验均不显著。总之，较高的柔韧性活动频率与老年人的 BP 降低有关。未来的纵向和干预研究应检查柔韧性活动对心血管疾病预防的影响。
