Dugas M, Halfon O, Nedey M C, Contamin E
Ann Med Interne (Paris). 1986;137(2):152-4.
A new type of anxiety state has recently been identified: the panic attack. This condition is qualitatively distinct from other anxiety disturbances and its treatment is different. Sodium lactate seems to play an essential role in the triggering of panic attacks through the intermediary of catabolic, physicochemical mechanisms or by alteration of adrenergic neurotransmission. Anxiety may be autonomised into two sub-groups, based on the effects of psychotropic drugs: phobic and anxiety states. The presence or absence of panic attacks is essential as it has diagnostic and therapeutic implications: M.A.D.I. or tricyclic antidepressors have a specific action on panic attacks but are ineffective on anticipatory, chronic, phobic or other forms of anxiety. Which are improved by benzodiazepines which; themselves, have very little effect on panic attacks.
惊恐发作。这种病症在性质上与其他焦虑障碍不同,其治疗方法也有所不同。乳酸钠似乎通过分解代谢、物理化学机制或通过改变肾上腺素能神经传递在引发惊恐发作中起重要作用。根据精神药物的作用,焦虑可分为两个亚组:恐惧症和焦虑状态。惊恐发作的有无至关重要,因为它具有诊断和治疗意义:单胺氧化酶抑制剂或三环类抗抑郁药对惊恐发作有特定作用,但对预期性、慢性、恐惧症或其他形式的焦虑无效。苯二氮䓬类药物可改善这些症状,而苯二氮䓬类药物本身对惊恐发作几乎没有作用。