Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Division of Clinical Pharmacology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Curr Allergy Asthma Rep. 2023 Jul;23(7):417-426. doi: 10.1007/s11882-023-01087-w. Epub 2023 May 16.
Adverse drug reactions (ADRs) are a significant cause of morbidity and mortality. The electronic health record (EHR) provides an opportunity to monitor ADRs, mainly through the utilization of drug allergy data and pharmacogenomics. This review article explores the current use of the EHR for ADR monitoring and highlights areas that require improvement.
Recent research has identified several issues with using EHR for ADR monitoring. These include the lack of standardization between EHR systems, specificity in data entry options, incomplete and inaccurate documentation, and alert fatigue. These issues can limit the effectiveness of ADR monitoring and compromise patient safety. The EHR has great potential for monitoring ADR but needs significant updates to improve patient safety and optimize care. Future research should concentrate on developing standardized documentation and clinical decision support systems within EHRs. Healthcare professionals should also be educated on the significance of accurate and complete ADR monitoring.
药物不良反应（ADR）是发病率和死亡率的重要原因。电子健康记录（EHR）为监测 ADR 提供了机会，主要通过利用药物过敏数据和药物基因组学来实现。本文综述了 EHR 在 ADR 监测中的当前应用，并强调了需要改进的领域。
最近的研究发现，使用 EHR 进行 ADR 监测存在几个问题。这些问题包括 EHR 系统之间缺乏标准化、数据录入选项的特异性、文档不完整和不准确以及警报疲劳。这些问题会限制 ADR 监测的有效性并危及患者安全。EHR 具有监测 ADR 的巨大潜力，但需要进行重大更新以提高患者安全性并优化护理。未来的研究应集中在开发 EHR 中的标准化文档和临床决策支持系统上。还应教育医疗保健专业人员准确和完整的 ADR 监测的重要性。
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