Zhu Wenwen, Guo Hui, Xu Jingjing, Wu Weiwei, Yi Yanmin, Wang Jiao, Duan Ran, Tong Jing, Du Yangguang
Xuzhou Municipal Center for Disease Control and Prevention, Xuzhou City, Jiangsu Province, China.
Xuzhou Municipal Tongshan District Center for Disease Control and Prevention, Xuzhou City, Jiangsu Province, China.
China CDC Wkly. 2023 Apr 7;5(14):311-314. doi: 10.46234/ccdcw2023.057.
WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: The largest and longest outbreak of diarrhea, which was complicated with hemolytic uremic syndrome (HUS) caused by enterohemorrhagic (EHEC) O157:H7, occurred in Xuzhou City and its adjacent areas from 1999 to 2000 in China.
WHAT IS ADDED BY THIS REPORT?: According to surveillance results from 2001 to 2021, there was a significant decrease in the isolation rate of O157:H7, and cattle and sheep remained the primary hosts. However, non-Shiga toxin-producing O157:H7 emerged as the dominant strain, with +- strains following closely behind.
WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: National surveillance of O157:H7 effectively serves as an early warning system and guidance for assessing the intensity and trend of disease epidemics. It is crucial to raise awareness of the public health risks associated with Shiga toxin-producing .
关于该主题已知的信息有哪些？：1999年至2000年，中国徐州市及其周边地区发生了由肠出血性大肠杆菌（EHEC）O157:H7引起的最大规模、持续时间最长的腹泻疫情，该疫情并发了溶血尿毒综合征（HUS）。
本报告新增了哪些内容？：根据2001年至2021年的监测结果，O157:H7的分离率显著下降，牛羊仍然是主要宿主。然而，非产志贺毒素的O157:H7成为优势菌株，+-菌株紧随其后。
对公共卫生实践有何启示？：对O157:H7的全国监测有效地作为一种早期预警系统，并为评估疾病流行强度和趋势提供指导。提高对产志贺毒素相关公共卫生风险的认识至关重要。
