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一例单心室、二尖瓣闭锁、房间隔完整且永存主静脉患者姑息性血管内治疗成功的临床病例。

A clinical case of successful palliative endovascular treatment of a patient with a single ventricle, mitral valve atresia, an intact atrial septum and persistent cardinal vein.

作者信息

Artem Gorbatykh, Denis Manannikov, Alina Ivanilova, Igor' Averkin, Dmitriy Zubarev, Aleksei Prokhorikhin, Ilya Soynov, Evgeniy Grekhov, Mikhail Chernyavskiy

机构信息

Almazov National Medical Research Centre, Akkuratova Str. 2, Saint-Petersburg, Russian Federation, 197341.

E.N. Meshalkin National Medical Research Centre, Rechkunovskaya Str. 15, Novosibirsk, Russian Federation, 630055.

出版信息

Egypt Heart J. 2023 May 18;75(1):41. doi: 10.1186/s43044-023-00368-z.

Abstract

BACKGROUND

Treatment of newborns with univentricular hemodynamics in combination with an anomaly of pulmonary venous return has the worst correction results in modern cardiac surgical papers. According to the data obtained by different authors, postoperative mortality in this cohort of patients varies from 41.7 to 53%. The presence of the venous outflow tract obstruction, as well as the serious condition of a newborn, is one of the main factors that increase the risk of death in the postoperative period.

CASE PRESENTATION

This article reveals a clinical case of a patient with a combined heart disease prenatally diagnosed in the form of a functionally single ventricle with a double outlet of the main vessels from it, mitral valve atresia, an intact atrial septum and an anomaly of venous return, when the blood outflow from the left atrium was carried out through a single fetal communication such as stenotic cardinal vein. In order to stabilize the patient's condition, the newborn urgently underwent stenting of the stenotic section of the cardinal vein. However, due to the lack of positive dynamics in the postoperative period, the child underwent repeated endovascular intervention and stenting of the intraoperatively created interatrial communication was performed. Taking into account the absence of obstruction of the outflow tract to the pulmonary artery, it was necessary to perform an open surgical intervention in a short time such as pulmonary artery banding.

CONCLUSIONS

Thus, palliative endovascular intervention in critically ill neonates with univentricular hemodynamics and anomalous pulmonary venous return can be considered as a method of choice that can become a new safer strategy for managing infants in order to stabilize the condition before the main stage of surgical intervention comes.

摘要

背景

在现代心脏外科文献中,对具有单心室血流动力学并伴有肺静脉回流异常的新生儿进行治疗,矫正效果最差。根据不同作者获得的数据,这类患者的术后死亡率在41.7%至53%之间。静脉流出道梗阻的存在以及新生儿的严重病情是增加术后死亡风险的主要因素之一。

病例介绍

本文揭示了一例产前诊断为复合型心脏病的临床病例,其表现为功能性单心室,主血管有双出口,二尖瓣闭锁,房间隔完整以及静脉回流异常,即左心房血液通过单一胎儿交通支如狭窄的主静脉流出。为稳定患者病情,新生儿紧急接受了主静脉狭窄段的支架置入术。然而,由于术后缺乏积极进展,患儿接受了再次血管内介入治疗,并对术中建立的房间隔交通支进行了支架置入。考虑到肺动脉流出道无梗阻,有必要在短时间内进行开放手术干预,如肺动脉环扎术。

结论

因此,对于患有单心室血流动力学和异常肺静脉回流的危重新生儿,姑息性血管内介入治疗可被视为一种选择方法,它可能成为管理婴儿的一种新的更安全策略,以便在手术干预的主要阶段到来之前稳定病情。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fcf/10195952/3872b68fafc8/43044_2023_368_Fig1_HTML.jpg

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