Department of Emergency Medicine, University of California Irvine School of Medicine, Orange.
Department of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut.
JAMA Netw Open. 2023 May 1;6(5):e2314848. doi: 10.1001/jamanetworkopen.2023.14848.
Alcohol use disorders have a high disease burden among US Latino groups. In this population, health disparities persist, and high-risk drinking has been increasing. Effective bilingual and culturally adapted brief interventions are needed to identify and reduce disease burden.
To compare the effectiveness of an automated bilingual computerized alcohol screening and intervention (AB-CASI) digital health tool with standard care for the reduction of alcohol consumption among US adult Latino emergency department (ED) patients with unhealthy drinking.
DESIGN, SETTING, AND PARTICIPANTS: This bilingual unblinded parallel-group randomized clinical trial evaluated the effectiveness of AB-CASI vs standard care among 840 self-identified adult Latino ED patients with unhealthy drinking (representing the full spectrum of unhealthy drinking). The study was conducted from October 29, 2014, to May 1, 2020, at the ED of a large urban community tertiary care center in the northeastern US that was verified as a level II trauma center by the American College of Surgeons. Data were analyzed from May 14, 2020, to November 24, 2020.
Patients randomized to the intervention group received AB-CASI, which included alcohol screening and a structured interactive brief negotiated interview in their preferred language (English or Spanish) while in the ED. Patients randomized to the standard care group received standard emergency medical care, including an informational sheet with recommended primary care follow-up.
The primary outcome was the self-reported number of binge drinking episodes within the last 28 days, assessed by the timeline followback method at 12 months after randomization.
Among 840 self-identified adult Latino ED patients (mean [SD] age, 36.2 [11.2] years; 433 [51.5%] male; and 697 [83.0%] of Puerto Rican descent), 418 were randomized to the AB-CASI group and 422 to the standard care group. A total of 443 patients (52.7%) chose Spanish as their preferred language at enrollment. At 12 months, the number of binge drinking episodes within the last 28 days was significantly lower in those receiving AB-CASI (3.2; 95% CI, 2.7-3.8) vs standard care (4.0; 95% CI, 3.4-4.7; relative difference [RD], 0.79; 95% CI, 0.64-0.99). Alcohol-related adverse health behaviors and consequences were similar between groups. The effect of AB-CASI was modified by age; at 12 months, the relative reduction in the number of binge drinking episodes within the last 28 days in the AB-CASI vs standard care group was 30% in participants older than 25 years (RD, 0.70; 95% CI, 0.54-0.89) compared with an increase of 40% in participants 25 years or younger (RD, 1.40; 95% CI, 0.85-2.31; P = .01 for interaction).
In this study, US adult Latino ED patients who received AB-CASI had a significant reduction in the number of binge drinking episodes within the last 28 days at 12 months after randomization. These findings suggest that AB-CASI is a viable brief intervention that overcomes known procedural barriers to ED screening, brief intervention, and referral to treatment and directly addresses alcohol-related health disparities.
ClinicalTrials.gov Identifier: NCT02247388.
在美国拉丁裔群体中,酒精使用障碍的疾病负担很高。在这一人群中,健康差距依然存在,高危饮酒的情况也在增加。需要有效的双语和文化适应的简短干预措施来识别和减少疾病负担。
比较自动化双语计算机酒精筛查和干预(AB-CASI)数字健康工具与标准护理在减少美国成年拉丁裔急诊(ED)患者不健康饮酒方面的效果。
设计、地点和参与者:这项双语非盲平行组随机临床试验评估了 AB-CASI 与标准护理在 840 名自我认定的有不健康饮酒行为的成年拉丁裔 ED 患者(代表了不健康饮酒的全部范围)中的有效性。该研究于 2014 年 10 月 29 日至 2020 年 5 月 1 日在一家东北部城市三级医疗中心的 ED 进行,该中心被美国外科医师学院确认为二级创伤中心。数据于 2020 年 5 月 14 日至 2020 年 11 月 24 日进行分析。
随机分配到干预组的患者接受 AB-CASI,包括在 ED 中用他们首选的语言(英语或西班牙语)进行酒精筛查和结构化互动式简短协商访谈。随机分配到标准护理组的患者接受标准的紧急医疗护理,包括一份推荐初级保健随访的信息表。
主要结果是通过时间线回溯法在随机分组后 12 个月内自我报告的过去 28 天内的 binge drinking 发作次数,以评估。
在 840 名自我认定的成年拉丁裔 ED 患者(平均[标准差]年龄,36.2[11.2]岁;433[51.5%]为男性;697[83.0%]为波多黎各人)中,418 名被随机分配到 AB-CASI 组,422 名被随机分配到标准护理组。共有 443 名患者(52.7%)在入组时选择西班牙语作为首选语言。在 12 个月时,接受 AB-CASI 的患者过去 28 天内 binge drinking 发作次数明显减少(3.2;95%CI,2.7-3.8),而接受标准护理的患者为 4.0(95%CI,3.4-4.7;相对差异[RD],0.79;95%CI,0.64-0.99)。两组的酒精相关不良健康行为和后果相似。AB-CASI 的效果受到年龄的影响;在 12 个月时,年龄大于 25 岁的患者中,AB-CASI 组与标准护理组相比,过去 28 天内 binge drinking 发作次数的相对减少为 30%(RD,0.70;95%CI,0.54-0.89),而年龄在 25 岁及以下的患者中,相对增加 40%(RD,1.40;95%CI,0.85-2.31;P 值为交互作用=.01)。
在这项研究中,接受 AB-CASI 的美国成年拉丁裔 ED 患者在随机分组后 12 个月时,过去 28 天内 binge drinking 发作次数显著减少。这些发现表明,AB-CASI 是一种可行的简短干预措施,它克服了 ED 筛查、简短干预和转介治疗的已知程序障碍,并直接解决了与酒精相关的健康差距。
ClinicalTrials.gov 标识符:NCT02247388。