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基于骨龄的双能X线吸收法测定慢性患者骨密度及其与实际年龄的比较

Determination of Bone Density by DEXA Method Based on Bone Age and its Comparison with Chronological Age in Chronic Patients.

作者信息

Katebi Leyla, Rabbani Ali, Sayarifard Fatemeh, Mehdizadeh Mehrzad, Sayarifard Azadeh, Sotoudeh Arya, Abbasi Farzaneh, Rostami Parastoo

机构信息

Department of Pediatrics, Faculty of Medicine, Ardabil University of Medical Science, Ardabil, Iran.

Department of Pediatrics, School of Medicine, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Mediterr J Rheumatol. 2023 Feb 21;34(1):44-52. doi: 10.31138/mjr.34.1.44. eCollection 2023 Mar.

Abstract

BACKGROUND AND OBJECTIVE

Given the growing awareness about the important role of children's age in building bone for a person's life, physicians need to assess bone health in high-risk children for bone density disorders more than before to optimize their bones' density and prevent osteoporosis in future. The aim of this study was to evaluate bone density based on chronological and bone age.

MATERIALS AND METHODS

In this cross-sectional study, 80 Patients who have been referred for bone density to the Osteoporosis Centre of the Children's Medical Centre over a one-year period (spring 98 to spring 99) were studied. Bone density was performed for all patients by using DEXA method.

RESULTS

The z-score mean chronological age for the lumbar spine was -0.8± 1.85 years and bone age was -0.58±1.64 years. The z-score mean chronological age for femoral bone was -1.6±1.02 years and bone age was -1.32± 1.4 years.

CONCLUSION

Results showed that in all patients, the difference in the mean Z score of chronological age and bone age of the spine between patients was not significant but for femur was significant. Also, use of corticosteroids leads to significant difference between the two age groups' z-score in femur and spine.

摘要

背景与目的

鉴于人们越来越意识到儿童年龄在构建一生的骨骼中所起的重要作用,医生比以往更需要评估骨密度紊乱高危儿童的骨骼健康,以优化其骨骼密度并预防未来的骨质疏松症。本研究的目的是根据实足年龄和骨龄评估骨密度。

材料与方法

在这项横断面研究中,对在一年期间(1998年春季至1999年春季)被转诊至儿童医学中心骨质疏松症中心进行骨密度检测的80例患者进行了研究。所有患者均采用双能X线吸收法(DEXA)进行骨密度检测。

结果

腰椎的实足年龄z评分均值为-0.8±1.85岁,骨龄为-0.58±1.64岁。股骨的实足年龄z评分均值为-1.6±1.02岁,骨龄为-1.32±1.4岁。

结论

结果显示,所有患者中,脊柱实足年龄和骨龄的平均Z评分差异不显著,但股骨的差异显著。此外,使用皮质类固醇导致两个年龄组在股骨和脊柱的z评分存在显著差异。

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3
Update on bone density measurements and their interpretation in children and adolescents.
Best Pract Res Clin Endocrinol Metab. 2018 Aug;32(4):477-498. doi: 10.1016/j.beem.2018.06.002. Epub 2018 Jun 18.
5
Bone age assessment methods: a critical review.
Pak J Med Sci. 2014 Jan;30(1):211-5. doi: 10.12669/pjms.301.4295.
6
Skeletal findings in children recently initiating glucocorticoids for the treatment of nephrotic syndrome.
Osteoporos Int. 2012 Feb;23(2):751-60. doi: 10.1007/s00198-011-1621-2. Epub 2011 Apr 15.
7
The use of bone age for bone mineral density interpretation in a cohort of pediatric brain tumor patients.
Pediatr Radiol. 2008 Dec;38(12):1285-92. doi: 10.1007/s00247-008-0991-x. Epub 2008 Sep 4.
9
Bone mineral density and bone acquisition in children and young adults with cystic fibrosis: a follow-up study.
J Pediatr Gastroenterol Nutr. 2004 Apr;38(4):401-6. doi: 10.1097/00005176-200404000-00007.
10
Evaluation of the possibility to assess bone age on the basis of DXA derived hand scans-preliminary results.
Osteoporos Int. 2004 Apr;15(4):317-22. doi: 10.1007/s00198-003-1545-6. Epub 2003 Nov 13.

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