Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
J Clin Psychiatry. 2023 May 22;84(4):22m14611. doi: 10.4088/JCP.22m14611.
Individuals with substance use disorders (SUDs) and co-occurring chronic health and/or psychiatric conditions face unique challenges in treatment and may be at a greater risk for suicidal ideation relative to persons with SUD alone. In a sample of individuals entering residential SUD treatment in 2019 and 2020 (N = 10,242), we tested adjusted and unadjusted associations between suicidal ideation and (1) psychiatric symptoms and (2) chronic health conditions at treatment intake and during treatment using logistic and generalized logistic models. Over a third of the sample endorsed suicidal ideation at intake, though the prevalence of suicidal ideation decreased during treatment. In both adjusted and unadjusted models, individuals who reported past-month self-harm, those who reported a lifetime suicide attempt, and individuals who screened positive for co-occurring anxiety, depression, and/or posttraumatic stress disorder were at elevated risk of endorsing suicidal ideation at intake and during treatment ( values < .001). In unadjusted models, chronic pain (odds ratio [OR] = 1.51, < .001) and hepatitis C virus (OR = 1.65, < .001) were associated with an elevated risk for suicidal ideation at intake, and chronic pain was associated with elevated risk for suicidal ideation during treatment (OR = 1.59, < .001). Increasing accessibility to integrated treatments (ie, those that address psychiatric and chronic health conditions) for patients experiencing suicidal ideation may be beneficial in residential SUD treatment settings. Developing predictive models to identify those most at risk of suicidal ideation in real time remains a relevant direction for future work.
患有物质使用障碍(SUD)且同时存在慢性健康和/或精神疾病的个体在治疗中面临独特的挑战,与仅患有 SUD 的个体相比,他们可能更有自杀意念的风险。在 2019 年和 2020 年进入住院 SUD 治疗的个体样本中(N=10242),我们使用逻辑和广义逻辑模型测试了自杀意念与(1)治疗开始时和治疗期间的精神症状和(2)慢性健康状况之间的调整和未调整关联。超过三分之一的样本在开始时表示有自杀意念,但自杀意念的发生率在治疗过程中下降。在调整和未调整模型中,报告过去一个月有自我伤害行为、报告有过自杀未遂经历、以及筛查出共病焦虑、抑郁和/或创伤后应激障碍的个体,在开始时和治疗期间报告自杀意念的风险增加(<0.001)。在未调整模型中,慢性疼痛(比值比 [OR] =1.51,<0.001)和丙型肝炎病毒(OR =1.65,<0.001)与开始时自杀意念风险增加相关,慢性疼痛与治疗期间自杀意念风险增加相关(OR =1.59,<0.001)。为有自杀意念的患者增加综合治疗(即,同时解决精神和慢性健康问题的治疗)的可及性,可能对住院 SUD 治疗环境有益。开发预测模型以实时识别那些最有自杀意念风险的人,仍然是未来工作的一个相关方向。