Alfin Jeneral Dumura, Shilong Danaan Joseph, Bot Gyang Markus, Nwibo Onyemaechi Ereke, Kyesmen Nanpan Isa, Olalere Shina Abidemi, Bakwa Nenkimun Dirting
Division of Neurosurgery, Department of Surgery, Jos University Teaching Hospital, Jos, Plateau State, Nigeria.
J West Afr Coll Surg. 2023 Apr-Jun;13(2):49-58. doi: 10.4103/jwas.jwas_200_22. Epub 2023 Mar 20.
BACKGROUND/OBJECTIVES: Spinal cord injury is a devastating condition and has been recognised so since antiquity with evolving pattern of presentation and outcome. This study aimed to review the clinical profile and determinants of early outcome in patients with traumatic spinal cord injury (TSCI) in Jos, Nigeria.
This retrospective cohort study, reviewed the health records of all patients with TSCI that were managed, based on the neurosurgical unit protocol for the management of TSCI in our institution from 2011 to 2021. Relevant data were retrieved into a preformed pro forma, analysis was done for determinants of outcome using SPSS and presented in tables and figure.
A total of 296 patients, aged 20-39 years, with male to female ratio of 5.2:1 were studied. The median time from injury to presentation was 96 h, and the cervical spine was the most (139, 47.0%) affected region. Most of the patients (183, 61.8%) had complete injury (ASIA A) at presentation, the average, first week mean arterial blood pressure (MAP) of 89.98 ± 8.86. Mortality was 73 (24.7%) at 6 weeks post injury and complete TSCI, cervical spinal cord segment and the average "first week" MAP were, independent predictors of mortality. The admission ASIA impairment scale (AIS) and injury to presentation interval were predictive of AIS improvement at 6 weeks and length of hospital stay (LOHs).
We also found that AIS at admission, level of spinal cord affected and the average first week MAP were early predictors of mortality, while the injury to presentation interval and admission AIS, predicted improvement of AIS at 6 weeks. The LOHs was seen more in patients with severe AIS at admission and those who had delayed presentation.
背景/目的:脊髓损伤是一种严重的疾病,自古以来就已被认识,其表现形式和预后不断演变。本研究旨在回顾尼日利亚乔斯市创伤性脊髓损伤(TSCI)患者的临床特征及早期预后的决定因素。
本回顾性队列研究,回顾了2011年至2021年期间在我院按照神经外科TSCI管理方案进行治疗的所有TSCI患者的健康记录。将相关数据录入预先设计的表格,使用SPSS对预后的决定因素进行分析,并以表格和图表形式呈现。
共研究了296例年龄在20 - 39岁之间的患者,男女比例为5.2:1。从受伤到就诊的中位时间为96小时,颈椎是受影响最严重的区域(139例,47.0%)。大多数患者(183例,61.8%)就诊时为完全性损伤(ASIA A级),伤后第一周平均动脉血压(MAP)为89.98±8.86。伤后6周死亡率为73例(24.7%),完全性TSCI、颈脊髓节段以及伤后第一周平均MAP是死亡率的独立预测因素。入院时ASIA损伤分级(AIS)和受伤至就诊间隔时间可预测伤后6周时AIS的改善情况及住院时间(LOHs)。
我们还发现,入院时的AIS、脊髓受累水平以及伤后第一周平均MAP是死亡率的早期预测因素,而受伤至就诊间隔时间和入院时AIS可预测伤后6周时AIS的改善情况。入院时AIS严重及就诊延迟的患者住院时间更长。