Bhattarai Himal Bikram, Rayamajhi Sushil, Bhattarai Madhur, Bhandari Sujata, Acharya Suryakiran, Uprety Manish, Yonghang Sapana, Kadel Gareema, Bhusal Sandhya, Joshi Sajeev
Gandaki Medical College, Teaching Hospital and Research Center, Pokhara.
Swacon International Hospital, Kathmandu.
Ann Med Surg (Lond). 2023 Apr 11;85(5):2145-2147. doi: 10.1097/MS9.0000000000000589. eCollection 2023 May.
Salmonella meningitis, caused by a Gram-negative bacillus of the Enterobacteriaceae family, is an uncommon but serious complication of Salmonella infection that can result in high mortality rates, significant neurological damage, and a high relapse rate, and has become a leading cause of Gram-negative bacterial meningitis in the developing world.
A 16-year-old boy presented with high-grade fever and altered sensorium for 2 days associated with vomiting, headache, and photophobia.
After invading the abdominal barrier, Salmonella can enter bloodstream and rarely present with meningitis. Cerebrospinal fluid analysis and culture supported with other investigations can diagnose bacterial meningitis and its causative agent. Adequate treatment is essential to completely cure and prevent relapse.
Given its invasive nature and potential serious consequences, such as relapse and antibiotic resistance, prompt, and appropriate treatment of Salmonella meningitis is essential.
沙门氏菌脑膜炎由肠杆菌科革兰氏阴性杆菌引起,是沙门氏菌感染罕见但严重的并发症,可导致高死亡率、严重神经损伤和高复发率,已成为发展中世界革兰氏阴性细菌性脑膜炎的主要病因。
一名16岁男孩出现高热和意识改变2天,伴有呕吐、头痛和畏光。
沙门氏菌侵入腹部屏障后可进入血液,很少引发脑膜炎。脑脊液分析和培养结合其他检查可诊断细菌性脑膜炎及其病原体。充分治疗对于彻底治愈和预防复发至关重要。
鉴于其侵袭性以及复发和抗生素耐药等潜在严重后果,及时、恰当治疗沙门氏菌脑膜炎至关重要。