Suppr超能文献

儿童偶然发现脑肿瘤的外科治疗:单中心经验

Surgical Treatment of Pediatric Incidentally Found Brain Tumors: A Single-Center Experience.

作者信息

Antkowiak Lukasz, Zimny Mikolaj, Starszak Krzysztof, Sordyl Ryszard, Mandera Marek

机构信息

Department of Pediatric Neurosurgery, Medical University of Silesia in Katowice, 40-752 Katowice, Poland.

Department of Neurosurgery, Medical University of Silesia in Katowice, 40-752 Katowice, Poland.

出版信息

Brain Sci. 2023 Apr 29;13(5):746. doi: 10.3390/brainsci13050746.

Abstract

There remains much debate about the correct management of incidentally found brain tumors in the pediatric population. This study aimed to evaluate the efficacy and safety of surgical treatment of incidentally found pediatric brain tumors. A retrospective analysis of pediatric patients who underwent surgical resection of incidentally found brain tumors between January 2010 and April 2016 was performed. A total of seven patients were included. The median age at the time of diagnosis was 9.7 years. The reasons for performing neuroimaging were as follows: impeded speech development ( = 2), shunt control ( = 1), paranasal sinuses control ( = 1), behavior changes ( = 1), head trauma ( = 1), and preterm birth ( = 1). Five patients underwent gross total tumor resection (71.4%), while subtotal resection was performed in two patients (28.6%). There was no surgery-related morbidity. Patients were followed up for a mean of 79 months. One patient with atypical neurocytoma experienced tumor recurrence 45 months following primary resection. All patients remained neurologically intact. The majority of pediatric incidentally found brain tumors were histologically benign. Surgery remains a safe therapeutic approach associated with favorable long-term outcomes. Considering the expected long lifetime of pediatric patients, as well as the psychological burden associated with having a brain tumor as a child, surgical resection can be considered an initial approach.

摘要

对于小儿群体中偶然发现的脑肿瘤的正确处理方式,仍存在诸多争议。本研究旨在评估手术治疗小儿偶然发现脑肿瘤的疗效和安全性。对2010年1月至2016年4月期间接受偶然发现脑肿瘤手术切除的小儿患者进行了回顾性分析。共纳入7例患者。诊断时的中位年龄为9.7岁。进行神经影像学检查的原因如下:言语发育受阻(2例)、分流控制(1例)、鼻窦检查(1例)、行为改变(1例)、头部外伤(1例)和早产(1例)。5例患者进行了肿瘤全切除(71.4%),2例患者进行了次全切除(28.6%)。无手术相关并发症。患者平均随访79个月。1例非典型神经细胞瘤患者在初次切除后45个月出现肿瘤复发。所有患者神经功能均保持完好。小儿偶然发现的脑肿瘤大多数在组织学上为良性。手术仍然是一种安全的治疗方法,具有良好的长期预后。考虑到小儿患者预期的较长寿命,以及儿童患脑肿瘤所带来的心理负担,手术切除可被视为一种初始治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47ed/10216312/e180c19119a6/brainsci-13-00746-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验