Department of Cardiology, Shamir Medical Center (Assaf Harofeh), Zerifin, Israel, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Department of Cardiology, Shamir Medical Center (Assaf Harofeh), Zerifin, Israel, Department of Anesthesiology, Shamir Medical Center (Assaf Harofeh), Zerifin, Israel.
Isr Med Assoc J. 2023 May;25(5):332-335.
Traditionally, transesophageal echocardiography (TEE) has been performed under moderate sedation and local pharyngeal anesthesia. Respiratory complications during the TEE can occur.
To test the effectiveness of low-dose midazolam combined with verbal sedation during TEE.
The study comprised 157 consecutive patients who underwent TEE under mild conscious sedation. All patients received local pharyngeal anesthesia and low doses of midazolam combined with verbal sedation. The course of TEE and clinical characteristics of the patients were analyzed.
The mean age was 64 ± 15.3 years, 96 males (61%). In 6% of the patients, low dose midazolam in combination with verbal sedation was insufficient and propofol was administrated. In women under 65 years of age with normal renal function, there was a 40% risk of low-dose midazolam being ineffective (P = 0.0018).
In most patients, TEE can be conducted easily using low-dose midazolam combined with verbal sedation. Some patients need deeper sedation with anesthetic agents like propofol. These patients tended to be younger, in good general health, and more often female.
传统上，经食管超声心动图（TEE）是在中度镇静和局部咽部麻醉下进行的。TEE 过程中可能会发生呼吸并发症。
测试小剂量咪达唑仑联合言语镇静在 TEE 中的有效性。
这项研究包括 157 例连续接受轻度清醒镇静下 TEE 的患者。所有患者均接受局部咽部麻醉和小剂量咪达唑仑联合言语镇静。分析 TEE 过程和患者的临床特征。
平均年龄为 64±15.3 岁，男性 96 例（61%）。在 6%的患者中，小剂量咪达唑仑联合言语镇静不足，需给予丙泊酚。在肾功能正常且年龄<65 岁的女性中，小剂量咪达唑仑无效的风险为 40%（P=0.0018）。
在大多数患者中，TEE 可以很容易地使用小剂量咪达唑仑联合言语镇静进行。一些患者需要使用麻醉剂如丙泊酚进行更深的镇静。这些患者往往更年轻，一般健康状况更好，且更多为女性。
Zotero 插件