感染患者的临床病理评估。

Clinicopathological Assesment in Patients with Infection.

机构信息

Amasya Üniversitesi Tıp Fakültesi, Patoloji Anabilim Dalı, Amasya, Türkiye

Amasya Üniversitesi Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Amasya, Türkiye

出版信息

Turkiye Parazitol Derg. 2023 Jun 29;47(2):93-99. doi: 10.4274/tpd.galenos.2023.02418.

DOI:10.4274/tpd.galenos.2023.02418

PMID:37249112

Abstract

OBJECTIVE

is a common gastrointestinal parasite. Acute appendicitis is one of the most common clinical conditions requiring surgical intervention. The coexistence of enterobiasis and acute appendicitis has attracted the attention of researchers for a long time. In this article, it is aimed to present the characteristics of enterobiasis cases detected in appendectomy specimens in a tertiary healthcare institution. In addition, it is aimed to reveal the differences by comparing the cases diagnosed with acute appendicitis without enterobiasis.

METHODS

All cases operated for acute appendicitis between January 1, 2008 and December 31, 2021 were retrospectively evaluated through the hospital registry system. The cases with histopathologically determined were reviewed and a study group was formed. The control group consisted of patients diagnosed with acute appendicitis for reasons other than enterobiasis, matched with the study group in terms of age and gender. Complete blood count, C-reactive protein (CRP) ultrasonography evaluations were compared between the two groups.

RESULTS

During the study period, 3.650 appendectomy materials were examined; was detected in 1.32% (n=48) cases, and acute appendicitis was present in 33.33% (n=16) of the cases. Lymphoid hyperplasia was the most common histopathological change in the study group (n=25; 52.08%). When compared to the control group, leukocyte, neutrophil, CRP, ultrasonographic appendix diameter values were found to be significantly higher in the control group, and the percentage of eosinophils in the study group (p<0.0001; p<0.0001; p<0.0001; p<0.0001; p=0.001; respectively).

CONCLUSION

Enterobiasis is a common parasite especially in children. Rarely, it can be seen in patients with acute appendicitis. Histopathological evaluation is necessary to ensure a safe surgical procedure and to complete the treatment with anthelmintic drugs. Enterobiasis should be kept in mind in cases when the acute phase response is lower than expected.

摘要

目的

是一种常见的胃肠道寄生虫。急性阑尾炎是最常见的需要手术干预的临床病症之一。肠虫病和急性阑尾炎的共存长期以来一直引起研究人员的关注。本文旨在介绍在一家三级保健机构的阑尾切除标本中检测到的肠虫病病例的特征。此外，还旨在通过比较诊断为无肠虫病的急性阑尾炎的病例来揭示差异。

方法

通过医院登记系统对 2008 年 1 月 1 日至 2021 年 12 月 31 日期间因急性阑尾炎接受手术的所有病例进行回顾性评估。对经组织病理学确定为的病例进行了回顾，并形成了一个研究组。对照组由因肠虫病以外的其他原因诊断为急性阑尾炎的患者组成，与研究组在年龄和性别方面相匹配。比较了两组的全血细胞计数、C 反应蛋白（CRP）超声评估。

结果

在研究期间，检查了 3650 个阑尾切除标本；在 1.32%（n=48）的病例中检测到，在 33.33%（n=16）的病例中存在急性阑尾炎。在研究组中，最常见的组织病理学改变是淋巴组织增生（n=25；52.08%）。与对照组相比，对照组的白细胞、中性粒细胞、CRP、超声阑尾直径值明显较高，研究组的嗜酸性粒细胞百分比也较高（p<0.0001；p<0.0001；p<0.0001；p<0.0001；p=0.001；分别）。