Emami Mohammadamin, Mirzamohamadi Sara, Heidari Amirhossein, Aein Afsaneh, Salarifar Mojtaba, Nematipour Ebrahim
Tehran Heart Center, Cardiovascular Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
J Tehran Heart Cent. 2023 Jan;18(1):68-71. doi: 10.18502/jthc.v18i1.12584.
Coronary artery disease (CAD) is the leading cause of cardiovascular death globally, and the most severe form of CAD, ST-elevation myocardial infarction (STEMI), needs immediate treatment. This study aimed to report patient characteristics and the causes of door-to-balloon time (D2BT) delays in STEMI patients admitted to Tehran Heart Center with a D2BT exceeding 90 minutes.
This cross-sectional study was conducted at Tehran Heart Center, Iran, from March 20th, 2020, through March 20th, 2022. Variables consisted of age, sex, diabetes mellitus, hypertension, dyslipidemia, smoking, opium, family history of CAD, in-hospital mortality, primary percutaneous coronary intervention results, culprit vessels, causes of delays, the ejection fraction, triglycerides, and low and high-density lipoprotein levels.
The study population was composed of 363 patients (272 males [74.9]) at a mean (SD) age of 60±11.47 years. The leading causes of D2BT delays were the catheterization lab used in 95 patients (26.2) and misdiagnosis in 90 (24.8). Other causes were ST-elevation less than 2 mm in electrocardiograms in 50 patients (13.8) and referral from other hospitals in 40 (11.0).
The catheterization lab in use and misdiagnosis were the leading causes of D2BT delays. We recommend that high-volume centers allocate an additional catheterization lab with an on-call cardiologist. Improved resident training and supervision in hospitals with many residents are also necessary.
冠状动脉疾病(CAD)是全球心血管死亡的主要原因,而CAD最严重的形式——ST段抬高型心肌梗死(STEMI)需要立即治疗。本研究旨在报告德黑兰心脏中心收治的门球时间(D2BT)超过90分钟的STEMI患者的特征及D2BT延迟的原因。
本横断面研究于2020年3月20日至2022年3月20日在伊朗德黑兰心脏中心进行。变量包括年龄、性别、糖尿病、高血压、血脂异常、吸烟、吸食鸦片、CAD家族史、院内死亡率、直接经皮冠状动脉介入治疗结果、罪犯血管、延迟原因、射血分数、甘油三酯以及低密度和高密度脂蛋白水平。
研究人群包括363例患者(272例男性[74.9%]),平均(标准差)年龄为60±11.47岁。D2BT延迟的主要原因是95例患者(26.2%)使用了导管室,90例患者(24.8%)误诊。其他原因包括50例患者(13.8%)心电图ST段抬高小于2毫米,40例患者(11.0%)从其他医院转诊。
使用的导管室和误诊是D2BT延迟的主要原因。我们建议大容量中心额外配备一个导管室并安排一名随叫随到的心脏病专家。在住院医师较多的医院,改善住院医师培训和监督也很有必要。