Division of Cardiovascular Intensive Care, Nippon Medical School Hospital.
Department of Cardiology and Intensive Care Unit, Nippon Medical School, Musashi-Kosugi Hospital.
Int Heart J. 2023;64(3):352-357. doi: 10.1536/ihj.22-656.
Although the primary percutaneous coronary intervention (PCI) is an established treatment for acute ST-elevation myocardial infarction (STEMI), relevant guidelines do not recommend it for recent-STEMI cases with a totally occluded infarcted related artery (IRA). However, PCI is allowed in Japan for recent-STEMI cases, but little is known regarding its outcomes. We aimed to examine the details and outcomes of PCI procedures in recent-STEMI cases with a totally occluded IRA and compared the findings with those in acute-STEMI cases.Among the 903 consecutive patients admitted with acute coronary syndrome, 250 were treated with PCI for type I STEMI with a totally occluded IRA. According to the time between symptom onset and diagnosis, patients were divided into the recent-STEMI (n = 32) and acute-STEMI (n = 218) groups. The background, procedure details, and short-term outcomes were analyzed. No significant differences between the groups were noted regarding patient demographics, acute myocardial infarction severity, or IRA distribution. Although the stent number and type were similar, significant differences were observed among PCI procedures, including the number of guidewires used, rate of microcatheter or double-lumen catheter use, and application rate of thrombus aspiration. The thrombolysis rate in the myocardial infarction flow 3-grade post-PCI did not differ significantly between the groups. Both groups had a low frequency of procedure-related complications. The in-hospital mortality rates were 0% and 4.6% in the recent-STEMI and acute-STEMI groups, respectively (P > 0.05).Although recent-STEMI cases required complicated PCI techniques, their safety, success rate, and in-hospital mortality were comparable to those of acute-STEMI cases.
尽管经皮冠状动脉介入治疗(PCI)是急性 ST 段抬高型心肌梗死(STEMI)的既定治疗方法,但相关指南并不推荐用于完全闭塞的梗死相关动脉(IRA)的近期 STEMI 病例。然而,日本允许对近期 STEMI 病例进行 PCI,但对于其结果知之甚少。我们旨在研究完全闭塞 IRA 的近期 STEMI 病例的 PCI 手术细节和结果,并将其与急性 STEMI 病例的结果进行比较。
在连续 903 例因急性冠状动脉综合征入院的患者中,有 250 例接受了 PCI 治疗完全闭塞 IRA 的 I 型 STEMI。根据症状发作和诊断之间的时间,将患者分为近期 STEMI(n = 32)和急性 STEMI(n = 218)组。分析了患者的背景、手术细节和短期结局。两组在患者人口统计学、急性心肌梗死严重程度或 IRA 分布方面无显著差异。尽管支架数量和类型相似,但 PCI 手术中存在显著差异,包括使用的导丝数量、微导管或双腔导管的使用率以及血栓抽吸的应用率。PCI 后心肌梗死血流 3 级的溶栓率在两组之间无显著差异。两组的手术相关并发症发生率均较低。近期 STEMI 组和急性 STEMI 组的住院死亡率分别为 0%和 4.6%(P > 0.05)。
尽管近期 STEMI 病例需要复杂的 PCI 技术,但它们的安全性、成功率和住院死亡率与急性 STEMI 病例相当。