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质子中心轴准直装置的设计、测试和特性分析用于动态准直系统。

Design, testing and characterization of a proton central axis alignment device for the dynamic collimation system.

机构信息

Department of Radiation Oncology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA, 52242, United States of America.

Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, United States of America.

出版信息

Biomed Phys Eng Express. 2023 Jun 13;9(4). doi: 10.1088/2057-1976/acdad5.

Abstract

. Proton therapy conformity has improved over the years by evolving from passive scattering to spot scanning delivery technologies with smaller proton beam spot sizes. Ancillary collimation devices, such the Dynamic Collimation System (DCS), further improves high dose conformity by sharpening the lateral penumbra. However, as spot sizes are reduced, collimator positional errors play a significant impact on the dose distributions and hence accurate collimator to radiation field alignment is critical.. The purpose of this work was to develop a system to align and verify coincidence between the center of the DCS and the proton beam central axis. The Central Axis Alignment Device (CAAD) is composed of a camera and scintillating screen-based beam characterization system. Within a light-tight box, a 12.3-megapixel camera monitors a P43/Gadox scintillating screen via a 45° first-surface mirror. When a collimator trimmer of the DCS is placed in the uncalibrated center of the field, the proton radiation beam continuously scans a 7×7 cmsquare field across the scintillator and collimator trimmer while a 7 s exposure is acquired. From the relative positioning of the trimmer to the radiation field, the true center of the radiation field can be calculated.The CAAD can calculate the offset between the proton beam radiation central axis and the DCS central axis within 0.054 mm accuracy and 0.075 mm reproducibility.Using the CAAD, the DCS is now able to be aligned accurately to the proton radiation beam central axis and no longer relies on an x-ray source in the gantry head which is only validated to within 1.0 mm of the proton beam.

摘要

. 质子治疗的适形度已经通过从被动散射演变为具有更小质子束斑点尺寸的点扫描输送技术得到了改善。辅助准直设备,如动态准直系统(DCS),通过锐化侧向半影进一步提高高剂量适形度。然而,随着斑点尺寸的减小,准直器位置误差对剂量分布有重大影响,因此精确对准准直器和辐射场至关重要。.. 这项工作的目的是开发一种系统,以对准和验证 DCS 中心与质子束中心轴之间的一致性。中央轴对准装置(CAAD)由相机和基于闪烁屏的束特性化系统组成。在一个不透光的盒子内,一台 1230 万像素的相机通过 45°第一表面反射镜监测一个 P43/Gadox 闪烁屏。当 DCS 的准直器调谐器放置在未校准的场中心时,质子辐射束连续扫描闪烁器和准直器调谐器上的 7×7 cmsquare 场,同时获取 7 秒的曝光。从调谐器与辐射场的相对定位,可以计算出辐射场的真实中心。CAAD 可以以 0.054 毫米的精度和 0.075 毫米的可重复性计算质子束辐射中心轴和 DCS 中心轴之间的偏移量。. 使用 CAAD,DCS 现在可以精确地对准质子辐射束中心轴,不再依赖于龙门头中的 X 射线源,该源仅在质子束内 1.0 毫米范围内得到验证。

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3
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8
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