Department of Orthopaedic Surgery, Tulane University School of Medicine, New Orleans, Louisiana.
OrthoCarolina Hip and Knee Center, Atrium Musculoskeletal Institute, Charlotte, North Carolina.
J Arthroplasty. 2024 Feb;39(2):441-447. doi: 10.1016/j.arth.2023.05.041. Epub 2023 Jun 2.
Studies have demonstrated increased complication risk after total hip arthroplasty (THA) in patients who smoke cigarettes. It is unclear if smokeless tobacco use confers a similar impact. The purpose of this study was to (1) evaluate rates of postoperative complications after THA in smokeless tobacco users and people who smoke compared to matched controls, and (2) compare rates of postoperative complications in smokeless tobacco users versus patients who smoke.
A retrospective cohort study was conducted using a large national database. For patients who underwent primary THA, smokeless tobacco users (n = 950) and people who smoke (n = 21,585) were matched 1:4 with controls (n = 3,800 and 86,340, respectively), and smokeless tobacco users (n = 922) were matched 1:4 with people who smoke (n = 3,688). Joint complication rates within 2 years and medical complications within 90 days postoperatively were compared using multivariable logistic regressions.
Within 90 days of primary THA, smokeless tobacco users demonstrated significantly higher rates of wound disruption, pneumonia, deep vein thrombosis, acute kidney injury (AKI), cardiac arrest, transfusion, readmission and longer length of stay compared to tobacco naïve controls. Within 2 years, smokeless tobacco users demonstrated significantly higher rates of prosthetic joint dislocations and overall joint-related complications compared to tobacco naïve controls.
Smokeless tobacco use is associated with higher rates of medical- and joint-related complications following primary THA. Smokeless tobacco use may be under-diagnosed in patients undergoing elective THA. Surgeons may consider delineating between smoking and smokeless tobacco use during preoperative counseling.
研究表明,吸烟患者行全髋关节置换术(THA)后并发症风险增加。目前尚不清楚使用无烟烟草是否会产生类似的影响。本研究的目的是:(1)评估 THA 术后使用无烟烟草和吸烟患者与匹配对照组相比术后并发症的发生率;(2)比较使用无烟烟草与吸烟患者术后并发症的发生率。
采用回顾性队列研究,使用大型国家数据库。对于接受初次 THA 的患者,将使用无烟烟草者(n=950)和吸烟者(n=21585)分别与对照组(n=3800 和 86340)进行 1:4 匹配,将使用无烟烟草者(n=922)与吸烟者(n=3688)进行 1:4 匹配。采用多变量逻辑回归比较术后 2 年内关节并发症发生率和术后 90 天内的医疗并发症发生率。
在初次 THA 后 90 天内,与烟草未使用者相比,使用无烟烟草者的切口裂开、肺炎、深静脉血栓形成、急性肾损伤(AKI)、心脏骤停、输血、再入院和住院时间延长的发生率明显更高。术后 2 年内,与烟草未使用者相比,使用无烟烟草者的人工关节脱位和整体关节相关并发症的发生率明显更高。
在初次 THA 后,使用无烟烟草与更高的医疗和关节相关并发症发生率相关。在接受择期 THA 的患者中,可能存在对使用无烟烟草的漏诊。外科医生在术前咨询时可能需要区分吸烟和使用无烟烟草。