From the Department of Radiology, University Hospital, LMU Munich, Munich, Germany.
Department of Nuclear Medicine, Medanta, Lucknow, India.
Clin Nucl Med. 2023 Aug 1;48(8):712-713. doi: 10.1097/RLU.0000000000004730. Epub 2023 Jun 6.
We present a rare case of a 74-year-old woman who underwent 68 Ga-DOTATOC PET/CT imaging for a suspected neuroendocrine tumor (NET) in the pancreatic head. PET/CT showed a solitary high somatostatis receptor (SSTR)-expressing lesion in the pancreatic head. Fine-needle aspiration of this lesion revealed a metastasis from a clear cell renal cell carcinoma (ccRCC). The patient had undergone nephrectomy 16 years prior due to ccRCC of the right kidney. Our case demonstrates that metastases originating from RCC can have high SSTR expression and therefore might mimic well-differentiated neuroendocrine tumors in 68 Ga-DOTATOC PET/CT.
我们报告了一例罕见病例，一名 74 岁女性因胰头部疑似神经内分泌肿瘤（NET）接受 68 Ga-DOTATOC PET/CT 成像。PET/CT 显示胰头部有一个孤立的高生长抑素受体（SSTR）表达病变。对该病变进行细针抽吸，发现来自透明细胞肾细胞癌（ccRCC）的转移。患者 16 年前因右肾 ccRCC 行肾切除术。我们的病例表明，源自 RCC 的转移灶可能具有高 SSTR 表达，因此在 68 Ga-DOTATOC PET/CT 中可能类似于分化良好的神经内分泌肿瘤。
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