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结直肠癌的放射学 T 分期:重新引起临床关注。

Radiologic T staging of colon cancer: renewed interest for clinical practice.

机构信息

Department of Radiology, Boston University Medical Center, Radiology- FGH 4001, 820 Harrison Ave, Boston, MA, 02118, USA.

Department of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

出版信息

Abdom Radiol (NY). 2023 Sep;48(9):2874-2887. doi: 10.1007/s00261-023-03904-2. Epub 2023 Jun 5.

Abstract

Radiologic imaging, especially MRI, has long been the mainstay for rectal cancer staging and patient selection for neoadjuvant therapy prior to surgical resection. In contrast, colonoscopy and CT have been the standard for colon cancer diagnosis and metastasis staging with T and N staging often performed at the time of surgical resection. With recent clinical trials exploring the expansion of the use of neoadjuvant therapy beyond the anorectum to the remainder of the colon, the current and future state of colon cancer treatment is evolving with a renewed interest in evaluating the role radiology may play in the primary T staging of colon cancer. The performance of CT, CT colonography, MRI, and FDG PET-CT for colon cancer staging will be reviewed. N staging will also be briefly discussed. It is expected that accurate radiologic T staging will significantly impact future clinical decisions regarding the neoadjuvant versus surgical management of colon cancer.

摘要

放射影像学检查,特别是 MRI,长期以来一直是直肠癌分期和新辅助治疗前患者选择的主要方法,然后再进行手术切除。相比之下,结肠镜检查和 CT 一直是结肠癌诊断和转移分期的标准方法,T 和 N 分期通常在手术切除时进行。最近的临床试验探讨了将新辅助治疗的应用范围从肛门直肠扩大到结肠的其余部分,因此目前和未来的结肠癌治疗正在发生变化,人们重新关注放射科在结肠癌原发 T 分期中可能发挥的作用。本文将对 CT、CT 结肠成像、MRI 和 FDG PET-CT 在结肠癌分期中的表现进行综述。N 分期也将简要讨论。预计准确的放射影像学 T 分期将对未来关于结肠癌新辅助治疗与手术治疗的临床决策产生重大影响。

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