Gao Zheng, Yue Yanyu, Zhang Youjia, Jiang Wentao, Zhang Yepeng, Ran Feng, Li Xiaoqiang
Department of Vascular Surgery, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, 2100082, People's Republic of China.
Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, 210008, People's Republic of China.
Int J Gen Med. 2023 May 31;16:2149-2156. doi: 10.2147/IJGM.S408609. eCollection 2023.
To study and compare the clinical outcomes of endovascular therapy with those of hybrid surgery in the treatment of Trans-Atlantic Inter-Society Consensus II (TASC II) D aortoiliac occlusive disease (AIOD).
Patients with TASC II D-type AIOD who underwent their first surgical treatment at our hospital between March 2018 and March 2021 were enrolled and followed up to evaluate the improvement in symptoms, complications, and primary patency. The Kaplan-Meier method was used to compare the differences in primary patency between the treatment groups.
In total, 132 of 139 enrolled patients (94.96%) achieved technical success following treatment. The perioperative mortality rate was 1.44% (2/139), and postoperative complications occurred in two patients. Among the patients who successfully underwent surgery, 120 underwent endovascular treatment (110 patients with stenting and 10 patients with thrombolysis before stenting), 10 underwent hybrid surgery, and 2 underwent open surgery. The follow-up data were compared between the endovascular and hybrid groups. At the end of the follow-up period, the patency rates in the hybrid and endovascular groups were 100% and 89.17% (107/120), respectively. The endovascular group achieved primary patency rates of 94.12%, 92.44%, and 89.08% at 6, 12, and 24 months postoperatively, respectively, whereas the primary patency rate remained at 100% in the hybrid group, with no significant variation between the endovascular and hybrid groups ( = 0.289). The endovascular group was further divided into a stent subgroup (110 patients) and a thrombolysis/stent subgroup (10 patients), and no prominent variation was noted in the primary patency between the two subgroups ( = 0.276).
Although open surgery is the gold standard treatment for TASC II D-type AIOD, endovascular and hybrid treatments are feasible and effective. Both methods showed good technical success and early to midterm primary patency rates.
研究并比较血管内治疗与杂交手术治疗跨大西洋两岸血管外科学会(TASC)II D型主髂动脉闭塞性疾病(AIOD)的临床疗效。
纳入2018年3月至2021年3月期间在我院接受首次手术治疗的TASC II D型AIOD患者,并进行随访,以评估症状改善情况、并发症及原发性通畅率。采用Kaplan-Meier法比较各治疗组原发性通畅率的差异。
139例纳入患者中,共有132例(94.96%)治疗后获得技术成功。围手术期死亡率为1.44%(2/139),2例患者出现术后并发症。成功接受手术的患者中,120例行血管内治疗(110例行支架置入术,10例行支架置入术前溶栓),10例行杂交手术,2例行开放手术。对血管内治疗组和杂交手术组的随访数据进行比较。随访期末,杂交手术组和血管内治疗组的通畅率分别为100%和89.17%(107/120)。血管内治疗组术后6、12和24个月的原发性通畅率分别为94.12%、92.44%和89.08%,而杂交手术组的原发性通畅率仍为100%,血管内治疗组和杂交手术组之间无显著差异(P = 0.289)。血管内治疗组进一步分为支架置入亚组(110例患者)和溶栓/支架置入亚组(10例患者),两组之间的原发性通畅率无显著差异(P = 0.276)。
虽然开放手术是TASC II D型AIOD的金标准治疗方法,但血管内治疗和杂交手术治疗也是可行且有效的。两种方法均显示出良好的技术成功率和早中期原发性通畅率。