Guha Debayan, Mendoza-Garcia Franz C, Millen Kathryn M, Offenbacher Joseph, Warstadt Nicholus M
Albert Einstein College of Medicine, Department of Emergency Medicine at the Jacobi and Montefiore Medical Centers, Bronx, New York.
New York University Grossman School of Medicine, Ronald O. Perelman Department of Emergency Medicine, New York, New York.
Clin Pract Cases Emerg Med. 2023 May;7(2):68-72. doi: 10.5811/cpcem.1404.
Wellens' syndrome represents an important, at times overlooked, spectrum of left anterior descending (LAD) coronary artery occlusion, spontaneous reperfusion, and impending reocclusion. Once considered pathognomonic for a thromboembolic coronary event, an increasing number of clinical scenarios have been demonstrated to result in pseudo-Wellens' syndrome, each requiring unique forms of assessment and management.
We describe two clinical presentations in which myocardial bridging (MB) of the LAD led to clinical and electrophysiologic presentations of a pseudo-Wellens' syndrome.
These reports represent a rare cause of pseudo-Wellens' syndrome attributed to MB of the LAD. Transient ischemia secondary to myocardial compression of the traversing LAD leads to intermittent angina and electrocardiogram changes that are typical in patients presenting with Wellens' syndrome secondary to an occlusive coronary event. As with other previously reported pathophysiologic mechanisms that have been shown to mimic Wellens' syndrome, myocardial bridging should be considered in patients presenting with a pseudo-Wellens' syndrome.
Wellens综合征代表了一种重要的、有时被忽视的左前降支(LAD)冠状动脉闭塞、自发再灌注和即将再次闭塞的情况。曾经被认为是血栓栓塞性冠状动脉事件的特征性表现,现在越来越多的临床情况被证明会导致假性Wellens综合征,每种情况都需要独特的评估和管理形式。
我们描述了两例临床病例,其中LAD的心肌桥(MB)导致了假性Wellens综合征的临床和电生理表现。
这些报告代表了一种罕见的假性Wellens综合征病因,归因于LAD的MB。横穿LAD的心肌受压继发的短暂性缺血导致间歇性心绞痛和心电图改变,这在因闭塞性冠状动脉事件继发Wellens综合征的患者中很典型。与其他先前报道的可模拟Wellens综合征的病理生理机制一样,对于表现为假性Wellens综合征的患者应考虑心肌桥。