Dąbrowski Emil Julian, Święczkowski Michał, Dudzik Joanna Maria, Grunwald Oliwia, Januszko Tomasz, Muszyński Paweł, Pogorzelski Piotr, Tokarewicz Justyna, Południewski Maciej, Kożuch Marcin, Dobrzycki Sławomir
Department of Invasive Cardiology, Medical University of Bialystok, 24A Sklodowskiej-Curie St., 15-276 Bialystok, Poland.
Second Department of Nephrology and Hypertension with Dialysis Unit, Medical University of Bialystok, 24A Sklodowskiej-Curie St., 15-276 Bialystok, Poland.
J Clin Med. 2023 May 30;12(11):3762. doi: 10.3390/jcm12113762.
In the aging society, the issue of coronary chronic total occlusion (CTO) has become a challenge for invasive cardiologists. Despite the lack of clear indications in European and American guidelines, the rates of percutaneous coronary interventions (PCI) for CTO increased over the last years. Well-conducted randomized clinical trials (RCT) and large observational studies brought significant and substantial progress in many CTO blind spots. However, the results regarding the rationale behind revascularization and the long-term benefit of CTO are inconclusive. Knowing the uncertainties regarding PCI CTO, our work sought to sum up and provide a comprehensive review of the latest evidence on percutaneous recanalization of coronary artery chronic total occlusion.
在老龄化社会中,冠状动脉慢性完全闭塞(CTO)问题已成为侵入性心脏病专家面临的一项挑战。尽管欧美指南中缺乏明确的适应症,但近年来CTO的经皮冠状动脉介入治疗(PCI)率仍有所上升。精心开展的随机临床试验(RCT)和大型观察性研究在许多CTO盲点方面取得了重大实质性进展。然而,关于血运重建背后的原理以及CTO的长期获益的结果尚无定论。鉴于PCI治疗CTO存在不确定性,我们的工作旨在总结并全面回顾冠状动脉慢性完全闭塞经皮再通的最新证据。