Dupuy Pierre, Gutierrez Claude, Neyrolles Olivier
Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.
Mol Microbiol. 2023 Oct;120(4):502-507. doi: 10.1111/mmi.15105. Epub 2023 Jun 11.
Recent research has demonstrated specific protein clustering within membrane subdomains in bacteria, challenging the long-held belief that prokaryotes lack these subdomains. This mini review provides examples of bacterial membrane protein clustering, discussing the benefits of protein assembly in membranes and highlighting how clustering regulates protein activity.
最近的研究表明,细菌的膜亚结构域内存在特定的蛋白质聚集现象,这挑战了长期以来认为原核生物缺乏这些亚结构域的观点。这篇小型综述提供了细菌膜蛋白聚集的实例,讨论了膜中蛋白质组装的益处,并强调了聚集如何调节蛋白质活性。