Cangemi David J, Lacy Brian E
Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL, USA.
Clin Exp Gastroenterol. 2023 Jun 6;16:65-78. doi: 10.2147/CEG.S362879. eCollection 2023.
Gastroparesis (GP), a historically vexing disorder characterized by symptoms of nausea, vomiting, abdominal pain, early satiety, and/or bloating, in the setting of an objective delay in gastric emptying, is often difficult to treat and carries a tremendous burden on the quality of patients' lives, as well as the healthcare system in general. Though the etiology of GP has been fairly well defined, much work has been done recently to better understand the pathophysiology of GP, as well as to identify novel effective and safe treatment options. As our understanding of GP has evolved, many myths and misconceptions still abound in this rapidly changing field. The goal of this review is to identify myths and misconceptions regarding the etiology, pathophysiology, diagnosis, and treatment of GP, in the context of the latest research findings which have shaped our current understanding of GP. Recognition and dispelling of such myths and misconceptions is critical to moving the field forward and ultimately advancing the clinical management of what will hopefully become a better understood and more manageable disorder in the future.
胃轻瘫(GP)是一种长期以来令人困扰的疾病,其特征为恶心、呕吐、腹痛、早饱及/或腹胀等症状,且存在胃排空客观延迟的情况。这种疾病往往难以治疗,给患者的生活质量以及整个医疗系统都带来了巨大负担。尽管胃轻瘫的病因已相当明确,但最近人们开展了大量工作,以更好地理解胃轻瘫的病理生理学,并确定新的有效且安全的治疗方案。随着我们对胃轻瘫的认识不断发展,在这个快速变化的领域中,仍存在许多误解和错误观念。本综述的目的是结合塑造了我们当前对胃轻瘫理解的最新研究结果,识别有关胃轻瘫病因、病理生理学、诊断和治疗的误解和错误观念。认识并消除这些误解和错误观念对于推动该领域的发展,并最终改善对这种有望在未来得到更好理解和更易管理的疾病的临床管理至关重要。