胃腺癌与MALT型淋巴瘤同步发生：一例报告及文献复习

Synchronous occurrence of gastric adenocarcinoma and MALT-type lymphoma: A case report and literature review.

作者信息

Phuong Vu-Thi, Lieu Dau Quang, Hanh Bui Thi My, Thu Hien Ha-Thi, Khanh Nguyen-Van, Hang Nguyen-Thi, Duc Nguyen Minh

机构信息

Department of Laboratory, Pathology Division, Vinmec Times City International Hospital, Hanoi, Vietnam.

Department of Internal Medicine, Hanoi Medical University Hospital, Hanoi, Vietnam.

出版信息

Radiol Case Rep. 2023 Jun 2;18(8):2730-2734. doi: 10.1016/j.radcr.2023.05.035. eCollection 2023 Aug.

DOI:10.1016/j.radcr.2023.05.035

PMID:37304315

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10250828/

Abstract

The coexistence of multiple primary malignant tumors in an organ is rare. This includes the extremely rarely reported combination of gastric adenocarcinoma and gastric MALT-type lymphoma as synchronous tumors. We describe a case of a 72-year-old man diagnosed with this combination. He had no remarkable medical history and came to our hospital because of discomfort in the gastric area. Although the biopsy revealed adenocarcinoma only, the microscopic findings after partial gastrectomy incidentally showed additional lymphoma that was subsequently confirmed by immunohistochemistry as MALT-type lymphoma. This case study and literature analysis aims to raise awareness of the possibility of synchronous malignant neoplasm in the stomach to enhance preoperative diagnosis.

摘要

一个器官内存在多种原发性恶性肿瘤的情况较为罕见。这包括极为罕见的胃腺癌与胃黏膜相关淋巴组织（MALT）型淋巴瘤同时发生的病例报道。我们描述了一名72岁男性被诊断为此种组合病例。他既往无显著病史，因胃部不适前来我院就诊。尽管活检仅显示为腺癌，但部分胃切除术后的显微镜检查结果意外发现了额外的淋巴瘤，随后经免疫组织化学证实为MALT型淋巴瘤。本病例研究及文献分析旨在提高对胃内同时发生恶性肿瘤可能性的认识，以加强术前诊断。