Department of Radiology, Shiga University of Medical Science Hospital, Seta-tsukinowa-cho, Otsu City, Shiga, 520-2192, Japan.
Division of Health Sciences, Osaka University Graduate School of Medicine, 1-7 Yamadaoka, Suita City, Osaka, 565-0871, Japan.
Ann Nucl Med. 2023 Aug;37(8):470-477. doi: 10.1007/s12149-023-01849-6. Epub 2023 Jun 12.
This study was aimed at determining the minimum acquisition count to provide diagnosable image quality (DIQ) and investigating the usefulness of preset count acquisition (PCA) for planar images of pediatric Tc-dimercaptosuccinic acid (DMSA) scintigraphy.
First, we calculated a coefficient of variation (CV) for DIQ with the shortest acquisition time through visual evaluation in 12 pediatric patients who underwent Tc-DMSA scintigraphy. Second, a minimum acquisition count to achieve the CV for DIQ was determined with the single regression analysis using CV as an explanatory variable and the total acquisition count as an objective variable in 81 pediatric patients. Finally, we compared PCA images based on the minimum acquisition count and preset time acquisition (PTA) images for 5 min in terms of the acquisition time, CV, and renal uptake ratio in another 23 pediatric patients.
The visual evaluation showed that the CV corresponding to DIQ with the shortest acquisition time was 27.1%. The total acquisition count corresponding to DIQ was revealed to be 299,764 in the single regression analysis and was determined to be 300,000 after rounding. The CV and its standard deviation in PCA at 300,000 counts and PTA for 5 min were 26.4 ± 0.6% and 24.8 ± 1.3%, respectively. The standard deviation of CV in PCA at 300,000 counts was smaller than that in PTA for 5 min, indicating little variation in image quality between cases. The acquisition time in PCA at 300,000 counts (3.1 ± 0.7 min) was shorter than that in PTA for 5 min (5.0 ± 0.0 min). The intraclass correlation coefficient between renal uptake ratios for PCA and PTA was 0.98, indicating an extremely high concordance.
The minimum acquisition count required for the DIQ was 300,000. In addition, PCA at 300,000 counts was demonstrated to be useful by providing stable image quality at the shortest acquisition time.
本研究旨在确定提供可诊断图像质量(DIQ)的最小采集计数,并探讨预设计数采集(PCA)在小儿 Tc-二巯丁二酸(DMSA)闪烁显像平面图像中的应用价值。
首先,我们通过 12 例接受 Tc-DMSA 闪烁显像的儿科患者的视觉评估计算出最短采集时间的 DIQ 变异系数(CV)。其次,通过单回归分析,使用 CV 作为解释变量,总采集计数作为目标变量,在 81 例儿科患者中确定达到 DIQ CV 的最小采集计数。最后,我们在 23 例儿科患者中比较了基于最小采集计数的 PCA 图像和预设时间采集(PTA)图像的采集时间、CV 和肾摄取率。
视觉评估显示,最短采集时间对应的 DIQ 的 CV 为 27.1%。单回归分析显示,DIQ 对应的总采集计数为 299764,四舍五入后确定为 300000。300000 计数的 PCA 和 5 分钟的 PTA 的 CV 及其标准差分别为 26.4±0.6%和 24.8±1.3%。300000 计数的 PCA 的 CV 标准差小于 5 分钟 PTA 的 CV 标准差,表明病例之间图像质量变化不大。300000 计数的 PCA 的采集时间(3.1±0.7 分钟)短于 5 分钟 PTA 的采集时间(5.0±0.0 分钟)。PCA 和 PTA 的肾摄取率的组内相关系数为 0.98,表明具有极高的一致性。
DIQ 所需的最小采集计数为 300000。此外,在最短采集时间内提供稳定的图像质量,证明 300000 计数的 PCA 是有用的。