Broekman Melle M, Brinkman Niels, Ramtin Sina, Ngoue Marielle, Ring David, Jayakumar Prakash
Department of Surgery and Perioperative Care, Dell Medical School at the University of Texas at Austin, Austin, TX, USA.
Chronic Stress (Thousand Oaks). 2023 Jun 8;7:24705470231179644. doi: 10.1177/24705470231179644. eCollection 2023 Jan-Dec.
Prior studies show that stressful life events are associated with greater magnitude of incapability and symptom intensity. We sought to understand the association of such events (i.e., both adverse childhood experiences recent difficult life events [DLEs]) alongside feelings of worry or despair and unhelpful, on the magnitude of incapability and symptom intensity in musculoskeletal patients. One hundred and thirty-six patients presenting for musculoskeletal specialty care completed measures of incapability, pain intensity, adverse childhood experiences, DLEs in the last year, unhelpful thoughts, symptoms of anxiety and depression, and sociodemographic factors. Factors associated with the magnitude of incapability and pain intensity were sought in multivariable analysis. Accounting for potential confounders, greater incapability was associated with greater unhelpful thoughts (RC = -0.81; 95% CI = -1.2 to -0.42; ≤ .001), but not with stressful life events (either during childhood or more recently). Greater pain intensity was associated with greater unhelpful thoughts(RC = 0.25; 95% CI = 0.16 to 0.35; ≤ .001) and being divorced or widowed (RC = 1.8; 96% CI = 0.43 to 3.2; = .011), but again, not with stressful life events. The strong association of unhelpful thoughts with magnitude of incapability and pain intensity can motivate musculoskeletal specialists to anticipate patients expressing negative pain thoughts and behaviors. Future studies might account for social and environmental context behind stressful life events and the influence of resiliency and pain-coping strategies on these interactions.
Level III, prognostic study.
先前的研究表明,应激性生活事件与更大程度的功能障碍和症状强度相关。我们试图了解此类事件(即童年不良经历和近期困难生活事件[DLEs])与担忧或绝望情绪以及无助感之间的关联,以及它们对肌肉骨骼疾病患者功能障碍程度和症状强度的影响。136名前来接受肌肉骨骼专科护理的患者完成了功能障碍、疼痛强度、童年不良经历、过去一年的DLEs、无助思维、焦虑和抑郁症状以及社会人口学因素的测量。在多变量分析中寻找与功能障碍程度和疼痛强度相关的因素。在考虑潜在混杂因素后,更大程度的功能障碍与更多的无助思维相关(相对变化量[RC] = -0.81;95%置信区间[CI] = -1.2至-0.42;P ≤.001),但与应激性生活事件(无论是童年时期还是近期)无关。更大的疼痛强度与更多的无助思维(RC = 0.25;95% CI = 0.16至0.35;P ≤.001)以及离婚或丧偶(RC = 1.8;96% CI = 0.43至3.2;P =.011)相关,但同样与应激性生活事件无关。无助思维与功能障碍程度和疼痛强度之间的强烈关联可能促使肌肉骨骼专科医生预测患者会表达消极的疼痛思维和行为。未来的研究可能需要考虑应激性生活事件背后的社会和环境背景,以及复原力和疼痛应对策略对这些相互作用的影响。
III级,预后研究。