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瑞典心脏停搏后重症监护:当前临床实践调查。

Post-cardiac arrest intensive care in Sweden: A survey of current clinical practice.

机构信息

School of Medical Sciences, University of Örebro, Örebro, Sweden.

Department of Anaesthesiology and Intensive Care Medicine, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

出版信息

Acta Anaesthesiol Scand. 2023 Oct;67(9):1249-1255. doi: 10.1111/aas.14298. Epub 2023 Jun 14.

Abstract

BACKGROUND

European guidelines recommend targeted temperature management (TTM) in post-cardiac arrest care. A large multicentre clinical trial, however, showed no difference in mortality and neurological outcome when comparing hypothermia to normothermia with early treatment of fever. The study results were valid given a strict protocol for the assessment of prognosis using defined neurological examinations. With the current range of recommended TTM temperatures, and applicable neurological examinations, procedures may differ between hospitals and the variation of clinical practice in Sweden is not known.

AIM

The aim of this study was to investigate current practice in post-resuscitation care after cardiac arrest as to temperature targets and assessment of neurological prognosis in Swedish intensive care units (ICUs).

METHODS

A structured survey was conducted by telephone or e-mail in all Levels 2 and 3 (= 53) Swedish ICUs during the spring of 2022 with a secondary survey in April 2023.

RESULTS

Five units were not providing post-cardiac arrest care and were excluded. The response rate was 43/48 (90%) of the eligible units. Among the responding ICUs, normothermia (36-37.7°C) was applied in all centres (2023). There was a detailed routine for the assessment of neurological prognosis in 38/43 (88%) ICUs. Neurological assessment was applied 72-96 h after return of spontaneous circulation in 32/38 (84%) units. Electroencephalogram and computed tomography and/or magnetic resonance imaging were the most common technical methods available.

CONCLUSION

Swedish ICUs use normothermia including early treatment of fever in post-resuscitation care after cardiac arrest and almost all apply a detailed routine for the assessment of neurological prognosis. However, available methods for prognostic evaluation varies between hospitals.

摘要

背景

欧洲指南建议在心脏骤停后护理中进行目标体温管理(TTM)。然而,一项大型多中心临床试验表明,在比较低温与常温并早期治疗发热时,死亡率和神经结局没有差异。研究结果是有效的,因为使用定义明确的神经检查对预后进行评估的严格方案。考虑到当前推荐的 TTM 温度范围以及适用的神经检查,医院之间的程序可能会有所不同,并且瑞典的临床实践变化尚不清楚。

目的

本研究旨在调查瑞典重症监护病房(ICU)中心脏骤停后复苏护理中目前的体温目标和神经预后评估情况。

方法

2022 年春季,通过电话或电子邮件对所有 2 级和 3 级(=53)瑞典 ICU 进行了一项结构化调查,并于 2023 年 4 月进行了二次调查。

结果

有 5 个单位不提供心脏骤停后护理,被排除在外。符合条件的单位中有 43/48(90%)做出了回应。在做出回应的 ICU 中,所有中心(2023 年)均采用正常体温(36-37.7°C)。38/43(88%)的 ICU 有详细的神经预后评估常规。32/38(84%)的单位在自主循环恢复后 72-96 小时进行神经评估。脑电图和计算机断层扫描和/或磁共振成像最常用的技术方法。

结论

瑞典 ICU 在心脏骤停后复苏护理中使用包括早期治疗发热的正常体温,几乎所有 ICU 都采用详细的神经预后评估常规。然而,医院之间的预后评估方法各不相同。

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