Qasim Abeer, Itare Vikram, Anwar Muhammad Yasir, Arguello Perez Esther
Internal Medicine, BronxCare Health System, Bronx, USA.
Infectious Disease, BronxCare Health System, Bronx, USA.
Cureus. 2023 May 16;15(5):e39098. doi: 10.7759/cureus.39098. eCollection 2023 May.
Kikuchi-Fujimoto disease (KFD) is an autoimmune condition that is more common in females and occurs in the third decade of life. The condition is usually benign and self-resolving and is characterized by fever, cervical lymphadenopathy, night sweats, myalgia, and rashes. The disease can be misdiagnosed as reactive follicular hyperplasia, tuberculous lymphadenitis, systemic lupus erythematosus, and malignant lymphoma. The diagnosis of KFD involves the excision of the affected lymph node. Although there is no specific treatment for the disease, usually symptomatic and supportive measures are effective; however, steroids and immunosuppressive therapies are considered in more severe cases. The disease lasts for around one to four months. The neurological complications include cerebellar ataxia, meningoencephalitis, and aseptic meningitis. Here, we describe the case of a 36-year-old male who presented with complaints of fever, malaise chills, anorexia, and fatigue associated with a tender right axillary lymph node. The patient underwent a biopsy which confirmed KFD and responded well to supportive therapy.
菊池-藤本病（KFD）是一种自身免疫性疾病，在女性中更为常见，发病于人生的第三个十年。该病通常为良性且可自行缓解，其特征为发热、颈部淋巴结病、盗汗、肌痛和皮疹。该疾病可能被误诊为反应性滤泡增生、结核性淋巴结炎、系统性红斑狼疮和恶性淋巴瘤。KFD的诊断需要切除受影响的淋巴结。虽然该病没有特效治疗方法，但通常对症和支持性措施是有效的；然而，在病情较严重的情况下会考虑使用类固醇和免疫抑制疗法。该病病程约为一至四个月。神经并发症包括小脑共济失调、脑膜脑炎和无菌性脑膜炎。在此，我们描述一名36岁男性的病例，他主诉发热、不适、寒战、厌食和疲劳，并伴有右侧腋窝淋巴结压痛。患者接受了活检，确诊为KFD，对支持性治疗反应良好。
