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老年成人非典型流感嗜血杆菌性骨髓炎和颈椎椎间盘炎:一例报告及文献综述

Non-typeable Haemophilus influenzae Osteomyelitis and Discitis of the Cervical Vertebrae in an Elderly Adult: A Case Report and Literature Review.

作者信息

Fong Jing Hong, Menon Shalisha Joy, Jones Gareth Iestyn Robert, Karunaratne Hettiyadura Apsara Surangani Mendis

机构信息

Department of General Medicine, North West Regional Hospital, Burnie, AUS.

Department of Medical Oncology, Albury Wodonga Health, Albury, AUS.

出版信息

Cureus. 2023 May 17;15(5):e39155. doi: 10.7759/cureus.39155. eCollection 2023 May.

Abstract

While  type B (Hib) is well described in the literature to cause osteomyelitis, non-typeable has not. In areas where vaccination is routine, the prevalence of Hib has declined, whereas, in contrast, the prevalence of non-typeable has increased. Generally, the non-typeable strains are less invasive but can access the vascular system by transmural migration through epithelial tight junctions or by an independent intercellular mechanism. Herein, we described a case of a 79-year-old man with the first case of non-typeable causing cervical osteomyelitis with associated bacteremia in an elderly adult.

摘要

虽然文献中已充分描述B型(b型流感嗜血杆菌)可引起骨髓炎,但不可分型菌株尚未见此报道。在常规接种疫苗的地区,b型流感嗜血杆菌的患病率有所下降,而相比之下,不可分型菌株的患病率却有所上升。一般来说,不可分型菌株的侵袭性较小,但可通过上皮紧密连接的透壁迁移或独立的细胞间机制进入血管系统。在此,我们描述了一例79岁男性患者,这是老年人中首例由不可分型菌株引起颈椎骨髓炎并伴有菌血症的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/079f/10275657/df374ab52593/cureus-0015-00000039155-i01.jpg

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