• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

使用骨移植替代物进行经皮踝关节融合后的临床结果

Clinical Outcomes Following Percutaneous Ankle Fusion With Bone Graft Substitute.

作者信息

Marciano Gerard F, Ferlauto Harrison R, Confino Jamie, Kelly Meghan, Surace Michele F, Vulcano Ettore

机构信息

Department of Orthopedics, Columbia University Medical Center, New York, NY, USA.

Department of Orthopedics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

出版信息

Foot Ankle Orthop. 2023 Jun 11;8(2):24730114231178781. doi: 10.1177/24730114231178781. eCollection 2023 Apr.

DOI:10.1177/24730114231178781
PMID:37332629
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10272655/
Abstract

BACKGROUND

Percutaneous ankle fusion is an emerging technique with minimal published outcome data. The goal of the present study is to retrospectively review clinical and radiographic outcomes following percutaneous ankle fusion and provide technique tips to perform percutaneous ankle fusion.

METHODS

Patients >18 years of age, treated by a single surgeon, from February 2018 to June 2021, who underwent primary isolated percutaneous ankle fusion supplemented with platelet-derived growth factor B (rhPDGF-BB) and beta-tricalcium phosphate, with at least 1-year follow-up were included. Surgical technique consisted of percutaneous ankle preparation followed by fixation with 3 headless compression screws. Pre- and postoperative visual analog scale (VAS) and Foot Function Index (FFI) were compared using paired tests. Fusion was assessed radiographically by the surgeon on postoperative radiographs and computed tomography (CT) at 3 months postoperatively.

RESULTS

Twenty-seven consecutive adult patients were included in the study. Mean follow-up was 21 months. Mean age was 59.8 years. Mean preoperative and postoperative VAS scores were 7.4 and 0.2, respectively ( < .01). Mean preoperative FFI pain domain, disability domain, activity restriction domain, and total score were 20.9, 16.7, 18.5, and 56.4, respectively. Mean postoperative FFI pain domain, disability domain, activity restriction domain, and total score were 4.3, 4.7, 6.7, and 15.8, respectively ( < .01). Fusion was achieved in 26 of 27 patients (96.3%) at 3 months. Four patients (14.8%) had complications.

CONCLUSION

We found in this cohort with surgery performed by a surgeon highly experienced in minimally invasive surgery that percutaneous ankle fusion augmented with a bone graft supplement achieved a high rate of fusion (96.3%) and a significant improvement in pain and function postoperatively while associated with minimal complications.

LEVEL OF EVIDENCE

Level IV, case series.

摘要

背景

经皮踝关节融合术是一种新兴技术,已发表的疗效数据极少。本研究的目的是回顾性分析经皮踝关节融合术后的临床和影像学结果,并提供经皮踝关节融合术的技术要点。

方法

纳入2018年2月至2021年6月期间由同一位外科医生治疗的年龄大于18岁的患者,这些患者接受了初次单纯经皮踝关节融合术,并补充了血小板衍生生长因子B(rhPDGF-BB)和β-磷酸三钙,且至少随访1年。手术技术包括经皮踝关节准备,然后用3枚无头加压螺钉固定。使用配对检验比较术前和术后视觉模拟量表(VAS)和足部功能指数(FFI)。术后3个月,由外科医生在术后X线片和计算机断层扫描(CT)上对融合情况进行影像学评估。

结果

本研究共纳入27例成年患者。平均随访时间为21个月。平均年龄为59.8岁。术前和术后VAS评分的平均值分别为7.4和0.2(<0.01)。术前FFI疼痛领域、残疾领域、活动受限领域和总分的平均值分别为20.9、16.7、18.5和56.4。术后FFI疼痛领域、残疾领域、活动受限领域和总分的平均值分别为4.3、4.7、6.7和15.8(<0.01)。27例患者中有26例(96.3%)在术后3个月实现了融合。4例患者(14.8%)出现并发症。

结论

在这个由一位在微创手术方面经验丰富的外科医生进行手术的队列中,我们发现补充骨移植的经皮踝关节融合术实现了较高的融合率(96.3%),术后疼痛和功能有显著改善,且并发症极少。

证据级别

IV级,病例系列。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dbd/10272655/c45e5c39f1b1/10.1177_24730114231178781-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dbd/10272655/2924bac4fc50/10.1177_24730114231178781-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dbd/10272655/dad5199af19c/10.1177_24730114231178781-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dbd/10272655/ac375e8b922c/10.1177_24730114231178781-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dbd/10272655/b77ec1c54ed7/10.1177_24730114231178781-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dbd/10272655/f9e8933c111c/10.1177_24730114231178781-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dbd/10272655/c45e5c39f1b1/10.1177_24730114231178781-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dbd/10272655/2924bac4fc50/10.1177_24730114231178781-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dbd/10272655/dad5199af19c/10.1177_24730114231178781-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dbd/10272655/ac375e8b922c/10.1177_24730114231178781-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dbd/10272655/b77ec1c54ed7/10.1177_24730114231178781-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dbd/10272655/f9e8933c111c/10.1177_24730114231178781-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9dbd/10272655/c45e5c39f1b1/10.1177_24730114231178781-fig6.jpg

相似文献

1
Clinical Outcomes Following Percutaneous Ankle Fusion With Bone Graft Substitute.使用骨移植替代物进行经皮踝关节融合后的临床结果
Foot Ankle Orthop. 2023 Jun 11;8(2):24730114231178781. doi: 10.1177/24730114231178781. eCollection 2023 Apr.
2
Prospective Randomized Controlled Trial of Hindfoot and Ankle Fusions Treated With rhPDGF-BB in Combination With a β-TCP-Collagen Matrix.rhPDGF-BB联合β-磷酸三钙-胶原基质治疗后足和踝关节融合的前瞻性随机对照试验
Foot Ankle Int. 2015 Jul;36(7):739-48. doi: 10.1177/1071100715576370. Epub 2015 Apr 6.
3
Recombinant Human Platelet-Derived Growth Factor BB in Combination With a Beta-Tricalcium Phosphate (rhPDGF-BB/β-TCP)-Collagen Matrix as an Alternative to Autograft.重组人血小板衍生生长因子 BB 与β-磷酸三钙(rhPDGF-BB/β-TCP)-胶原基质联合应用作为自体移植物的替代物。
Foot Ankle Int. 2019 Sep;40(9):1068-1078. doi: 10.1177/1071100719851468. Epub 2019 Jun 7.
4
Prospective, randomized, multi-center feasibility trial of rhPDGF-BB versus autologous bone graft in a foot and ankle fusion model.前瞻性、随机、多中心可行性试验:rhPDGF-BB 与自体骨移植物在足踝融合模型中的比较。
Foot Ankle Int. 2011 Apr;32(4):344-54. doi: 10.3113/FAI.2011.0344.
5
A retrospective review of recombinant human platelet-derived growth factor with beta-tricalcium phosphate bone graft substitute use in hindfoot and/or ankle arthrodesis.对重组人血小板衍生生长因子联合β-磷酸三钙骨移植替代物用于后足和/或踝关节融合术的回顾性研究。
J Orthop. 2023 Sep 9;44:93-98. doi: 10.1016/j.jor.2023.09.005. eCollection 2023 Oct.
6
Tibiotalocalcaneal arthrodesis with headless compression screws.采用无头加压螺钉的胫距跟关节融合术
J Orthop Surg Res. 2016 Aug 19;11(1):91. doi: 10.1186/s13018-016-0425-7.
7
Ankle Arthrodesis Through a Fibular-Sparing Anterior Approach.经腓骨保留前入路踝关节融合术。
Foot Ankle Int. 2020 Dec;41(12):1480-1486. doi: 10.1177/1071100720946740. Epub 2020 Aug 7.
8
Endoscopic Gastrocnemius Recession for the Treatment of Isolated Gastrocnemius Contracture: A Prospective Study on 320 Consecutive Patients.内镜下腓肠肌松解术治疗单纯性腓肠肌挛缩:对320例连续患者的前瞻性研究
Foot Ankle Int. 2014 Aug;35(8):747-756. doi: 10.1177/1071100714534215. Epub 2014 May 21.
9
[Minimally Invasive Posterior Lumbar Interbody Fusion and Instrumentation - Outcomes at 24-Month Follow-up].[微创后路腰椎椎间融合术及内固定术——24个月随访结果]
Acta Chir Orthop Traumatol Cech. 2020;87(2):95-100.
10
Optimal Outcomes for Acute Avulsion Fracture of the Achilles Tendon Treated With the Insertional Reattachment Technique: A Case Series of 31 Cases With Over 2 Years of Follow-up.采用插入式再固定技术治疗急性跟腱撕脱骨折的最佳结果:31 例超过 2 年随访的病例系列研究。
Am J Sports Med. 2019 Oct;47(12):2993-3001. doi: 10.1177/0363546519869952. Epub 2019 Sep 3.

引用本文的文献

1
The efficacy of shoes modification and orthotics in hallux valgus deformity: a comprehensive review of literature.鞋子改良和矫形在拇趾外翻畸形中的疗效:文献综合评价。
Musculoskelet Surg. 2024 Dec;108(4):395-402. doi: 10.1007/s12306-024-00839-9. Epub 2024 Jun 26.

本文引用的文献

1
Arthroscopic Versus Open Ankle Arthrodesis: A 5-Year Follow Up.关节镜下与开放性踝关节融合术:5 年随访结果。
J Bone Joint Surg Am. 2022 Jul 6;104(13):1197-1203. doi: 10.2106/JBJS.21.01088. Epub 2022 May 23.
2
Quality of MIS vs Open Joint Preparations of the Foot and Ankle.微创与开放关节准备在足踝手术中的质量比较。
Foot Ankle Int. 2022 Jul;43(7):948-956. doi: 10.1177/10711007221081865. Epub 2022 Apr 5.
3
Clinical effectiveness of arthroscopic vs open ankle arthrodesis for advanced ankle arthritis: A systematic review and meta-analysis.
关节镜与开放式踝关节融合术治疗晚期踝关节关节炎的临床疗效:系统评价和荟萃分析。
Medicine (Baltimore). 2021 Mar 12;100(10):e24998. doi: 10.1097/MD.0000000000024998.
4
Open versus arthroscopic ankle arthrodesis: a systematic review and meta-analysis.关节镜下踝关节融合术与开放式踝关节融合术的比较:系统评价和荟萃分析。
J Orthop Surg Res. 2020 May 24;15(1):187. doi: 10.1186/s13018-020-01708-4.
5
Clinical outcomes comparing arthroscopic vs open ankle arthrodesis.关节镜与开放式踝关节融合术的临床疗效比较。
Foot Ankle Surg. 2020 Jul;26(5):530-534. doi: 10.1016/j.fas.2019.06.004. Epub 2019 Jun 20.
6
A literature review of the complications following anterior and posterior ankle arthroscopy.踝关节前后关节镜检查后并发症的文献综述。
Foot Ankle Surg. 2019 Oct;25(5):553-558. doi: 10.1016/j.fas.2018.06.007. Epub 2018 Jul 18.
7
Arthroscopic Ankle Arthrodesis: A 2-15 Year Follow-up Study.关节镜下踝关节融合术:2-15 年随访研究。
Arthroscopy. 2018 May;34(5):1641-1649. doi: 10.1016/j.arthro.2017.11.031. Epub 2018 Feb 1.
8
Ankle arthrodesis-Open versus arthroscopic: A systematic review and meta-analysis.踝关节融合术——开放手术与关节镜手术:一项系统评价与荟萃分析
J Clin Orthop Trauma. 2017 Nov;8(Suppl 2):S71-S77. doi: 10.1016/j.jcot.2017.03.010. Epub 2017 Apr 6.
9
Factors Affecting the Outcomes of Uncomplicated Primary Open Ankle Arthrodesis.影响单纯性原发性开放性踝关节融合术预后的因素。
Foot Ankle Int. 2015 Oct;36(10):1170-9. doi: 10.1177/1071100715587045. Epub 2015 May 20.
10
Arthroscopic ankle arthrodesis.关节镜下踝关节融合术
Clin Podiatr Med Surg. 2011 Jun;28(3):511-21. doi: 10.1016/j.cpm.2011.04.008.