[实验性感染的电子显微镜研究。II. 志贺氏菌感染动态的研究]

[Electron microscopic study of experimental infection. II. A study of the dynamics of Shigella infection].

作者信息

Korinteli V I, Meĭpariani A N, Chanishvili T G, Darsavelidze M A, Burduli E V

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1979 Mar(3):40-2.

Abstract

The dynamics of experimental Shigella infection of chick embryo fibroblasts was studied with the use of electron microscopy. The antibiotic-resistant forms of Sh. sonnei 1,188 was found to be incapable of invasion into the fibroblast cytoplasm and intracellular proliferation. The destruction of fibroblasts observed during the infection was seemingly caused by the action of bacterial endotoxins.

摘要

利用电子显微镜研究了鸡胚成纤维细胞实验性志贺氏菌感染的动态过程。发现宋内志贺氏菌1188的抗生素抗性形式无法侵入成纤维细胞质并在细胞内增殖。感染期间观察到的成纤维细胞破坏似乎是由细菌内毒素的作用引起的。