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中国银屑病患者中银屑病关节炎的患病率:由经验丰富的风湿病学家进行的一项多中心研究。

Prevalence of psoriatic arthritis in Chinese population with psoriasis: A multicenter study conducted by experienced rheumatologists.

机构信息

Department of Rheumatology and Immunology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.

Department of Dermatology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine School of Medicine, Shanghai 200025, China.

出版信息

Chin Med J (Engl). 2023 Jun 20;136(12):1439-1447. doi: 10.1097/CM9.0000000000002683. Epub 2013 May 16.

DOI:10.1097/CM9.0000000000002683
PMID:37334732
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10278692/
Abstract

BACKGROUND

Reports on the prevalence of psoriatic arthritis (PsA) among Chinese patients with psoriasis are very limited. This study, conducted by rheumatologists, estimated the prevalence of PsA in a large number of Chinese patients with psoriasis.

METHODS

Consecutive patients with a confirmed diagnosis of psoriasis attending nine dermatology clinics in five hospitals were recruited. All psoriasis patients were asked to complete a questionnaire comprising 16 questions to identify possible cases of PsA. All patients with one or more positive answers to the questionnaire were evaluated by two experienced rheumatologists.

RESULTS

A total of 2434 psoriasis patients, including 1561 males and 873 females, were enrolled. Both the questionnaire and rheumatologists' examinations were completed in the dermatology clinics. The results identified 252 patients with PsA, comprising 168 males and 84 females. The overall prevalence of PsA among psoriasis patients was 10.4% (95% confidence interval [95% CI], 9.1%-11.7%). By sex, the prevalence was 10.8% (95% CI, 9.2%-12.5%) for males and 9.6% (95% CI, 7.7%-11.9%) for females and there was no significant sex difference in the prevalence of PsA (P = 0.38). Of the 252 PsA patients, 125 (49.6%, 95% CI, 41.3%-59.1%) were newly diagnosed by rheumatologists. Consequently, the prevalence of undiagnosed PsA among psoriasis patients was 5.2% (95% CI, 4.4%-6.2%).

CONCLUSION

The prevalence of PsA in the Chinese population with psoriasis is about 10.4%, which is almost double that of previous reports in the Chinese population, but lower than that in Caucasians.

摘要

背景

关于中国银屑病患者中银屑病关节炎(PsA)的患病率的报告非常有限。本研究由风湿病学家进行,旨在估计大量中国银屑病患者中 PsA 的患病率。

方法

连续招募了在五家医院的九家皮肤科诊所就诊的确诊为银屑病的患者。所有银屑病患者均需完成一份包含 16 个问题的问卷,以确定可能患有 PsA 的病例。所有对问卷有一个或多个阳性答案的患者均由两名经验丰富的风湿病学家进行评估。

结果

共纳入 2434 例银屑病患者,包括 1561 名男性和 873 名女性。问卷调查和风湿病学家检查均在皮肤科诊所完成。结果发现 252 例患有 PsA 的患者,包括 168 名男性和 84 名女性。银屑病患者中 PsA 的总体患病率为 10.4%(95%可信区间[95%CI],9.1%-11.7%)。按性别划分,男性患病率为 10.8%(95%CI,9.2%-12.5%),女性为 9.6%(95%CI,7.7%-11.9%),性别之间 PsA 的患病率无显著差异(P=0.38)。在 252 例 PsA 患者中,125 例(49.6%,95%CI,41.3%-59.1%)由风湿病学家新诊断。因此,银屑病患者中未确诊的 PsA 的患病率为 5.2%(95%CI,4.4%-6.2%)。

结论

中国银屑病人群中 PsA 的患病率约为 10.4%,几乎是中国人群先前报告的两倍,但低于白种人。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0700/10278692/b53b1c722c2d/cm9-136-1439-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0700/10278692/e7db24dee5df/cm9-136-1439-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0700/10278692/cce91ad761bf/cm9-136-1439-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0700/10278692/b53b1c722c2d/cm9-136-1439-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0700/10278692/e7db24dee5df/cm9-136-1439-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0700/10278692/cce91ad761bf/cm9-136-1439-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0700/10278692/b53b1c722c2d/cm9-136-1439-g003.jpg

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