Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, Pakistan.
J Cosmet Dermatol. 2023 Dec;22(12):3480-3490. doi: 10.1111/jocd.15865. Epub 2023 Jun 19.
Pharmacological properties of Quercus infectoria Olivier (galls) have been determined to be astringent, antidiabetic, antipyretic, anti-tremor, local anesthetic, and anti-parkinsonism. The galls of Quercus infectoria have been used for millennia in traditional oriental medicine in Asian nations to treat inflammatory illnesses.
The study's objective was to create a Quercus infectoria Olivier gall extract in stable water in oil (w/o) emulsion and to check its effects on the mechanical properties of skin and antiaging effects.
The galls were macerated in absolute methanol. Quercus infectoria Olivier gall extract's antioxidant property was evaluated using the 2, 2-diphenyl-1-picrylhydrazyl (DPPH) technique. Stearic acid, cetyl alcohol, KOH, glycerin, and distilled water were used to create the emulsion. The test (with extract) and control (without extract) emulsions were made, respectively, using the same process. Stability tests (color, liquefaction, microscopy, phase separation, and pH) are performed in in vitro, lasted 72 days at four distinct storage temperatures that is 8°C, 25°C, 40°C, and 40°C + 75% RH for both the control and test formulations. By using spectrophotometry, the (SPF) sun protection factors of the two formulations were calculated at various concentrations. Extract from Quercus infectoria underwent phytochemical investigation as well.
The results showed that Quercus infectoria Olivier has antioxidant and (SPF) sun protection properties, reduce sebum, increases elasticity and stable emulsion containing 04% Quercus infectoria gall extract which might be used as topical antiaging formulation.
栎瘿(Quercus infectoria Olivier 的虫瘿)的药理学特性已被确定为收敛、抗糖尿病、退热、抗震颤、局部麻醉和抗帕金森病。栎瘿在亚洲国家的传统东方医学中已被使用了数千年,用于治疗炎症性疾病。
本研究的目的是制备栎瘿稳定的油包水(w/o)乳液提取物,并检查其对皮肤机械性能的影响和抗老化作用。
栎瘿用无水甲醇浸渍。使用 2,2-二苯基-1-苦基肼基(DPPH)法评估栎瘿提取物的抗氧化性能。使用硬脂酸、十六醇、KOH、甘油和蒸馏水制备乳液。分别使用相同的工艺制备测试(含提取物)和对照(无提取物)乳液。在体外进行稳定性测试(颜色、液化、显微镜检查、相分离和 pH),在四个不同的储存温度下持续 72 天,分别为 8°C、25°C、40°C 和 40°C+75% RH,对对照和测试制剂进行测试。使用分光光度法计算两种制剂在不同浓度下的(SPF)防晒因子。栎瘿提取物还进行了植物化学研究。
结果表明,栎瘿具有抗氧化和(SPF)防晒性能,减少皮脂,增加弹性,并且含有 04%栎瘿虫瘿提取物的稳定乳液可用于局部抗老化制剂。