揭示干细胞的奥秘：光遗传学揭示 ERK 动力学在多能性中的作用。
Shedding light on stem cells: Optogenetics uncover the role of ERK dynamics in pluripotency.
机构信息
Department of Cell and Developmental Biology, Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; University College London, WC1E 6BT London, UK.
Department of Cell and Developmental Biology, Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
出版信息
Dev Cell. 2023 Jun 19;58(12):1005-1006. doi: 10.1016/j.devcel.2023.05.016.
In this issue of Developmental Cell, Arekatla et al. use optogenetic technologies to dissect the roles of ERK and AKT dynamics in pluripotency. They show how mouse embryonic stem cells can retain memory of signaling events controlling their fate.
在本期《发育细胞》中，Arekatla 等人利用光遗传学技术来剖析 ERK 和 AKT 动力学在多能性中的作用。他们展示了小鼠胚胎干细胞如何能够保留控制其命运的信号事件的记忆。
Zotero 插件