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面部整形外科医生的转化研究技术:概述。

Translational Research Techniques for the Facial Plastic Surgeon: An Overview.

机构信息

Department of Otolaryngology, Henry Ford Hospital, Detroit, Michigan.

Department of Public Health Science, Henry Ford Health, Detroit, Michigan.

出版信息

Facial Plast Surg. 2023 Oct;39(5):466-473. doi: 10.1055/a-2113-5023. Epub 2023 Jun 20.

Abstract

The field of facial plastic and reconstructive surgery (FPRS) is an incredibly diverse, multispecialty field that seeks innovative and novel solutions for the management of physical defects on the head and neck. To aid in the advancement of medical and surgical treatments for these defects, there has been a recent emphasis on the importance of translational research. With recent technological advancements, there are now a myriad of research techniques that are widely accessible for physician and scientist use in translational research. Such techniques include integrated multiomics, advanced cell culture and microfluidic tissue models, established animal models, and emerging computer models generated using bioinformatics. This study discusses these various research techniques and how they have and can be used for research in the context of various important diseases within the field of FPRS.

摘要

面部整形和重建外科(FPRS)领域是一个非常多样化的多学科领域,它为头部和颈部的身体缺陷的管理寻求创新和新颖的解决方案。为了帮助推进这些缺陷的医学和手术治疗,最近强调了转化研究的重要性。随着最近技术的进步,现在有许多研究技术广泛可供医生和科学家在转化研究中使用。这些技术包括集成多组学、先进的细胞培养和微流控组织模型、已建立的动物模型以及使用生物信息学生成的新兴计算机模型。本研究讨论了这些各种研究技术以及它们如何已经并且可以用于 FPRS 领域内各种重要疾病的研究。

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