Khamseh Fatemah, Hadjati Gholamreza, Nahvinejad Hossein, Nouparast Zahra, Salehi Masomeh, Noroozian Maryam, Foroughan Mahshid, Alaedini Farshid, Saffarifard Afrooz, Farin Faraneh, Khansari Mehrdad, Pourseid Mohammad Maryam, Ahmadi Zahra
Iranian Association of Alzheimer's Disease, Tehran, Iran.
Iranian State Welfare Organization, Tehran, Iran.
Basic Clin Neurosci. 2023 Jan-Feb;14(1):137-142. doi: 10.32598/bcn.2022.1745.1. Epub 2023 Jan 1.
This study aimed to compare the diagnostic value of four questionnaires for the diagnosis of neurocognitive disorders (NCDs) in the elderly.
In this project, people older than 60 years who lived in Tehran were investigated. A total of 99 literate cases were enrolled in the study, and four questionnaires, including functional assessment staging tool (FAST), abbreviated mental test score (AMTS), mini-mental state examination (MMSE), and modified Persian test of elderly for assessment of cognition and executive function (PEACE) were completed for them. They were then referred to a neuropsychiatrist, and the status of their cognition and neurobehavior was determined. The specialists were blinded to the results of the tests.
Of the 99 participants studied, 39 cases were healthy, eight cases had mild Alzheimer's disease, 38 had amnesic MCI, five cases had secondary dementia, and nine cases had mixed vascular dementia and Alzheimer's disease. The area under the ROC curve for distinguishing the healthy group from the rest of the population was 0.692, 0.629, 0.734, and 0.751 for the FAST, AMTS, MMSE, and NBCSS questionnaires, respectively.
MMSE and NBCSS tests had better diagnostic power than the other two tests to distinguish the healthy group from the rest of the population.
本研究旨在比较四种问卷对老年人神经认知障碍（NCDs）的诊断价值。
在该项目中，对居住在德黑兰的60岁以上人群进行了调查。共有99名识字的受试者纳入研究，为他们完成了四种问卷，包括功能评估分期工具（FAST）、简易精神状态检查表（AMTS）、简易精神状态检查（MMSE）以及用于评估认知和执行功能的改良波斯老年人测试（PEACE）。然后他们被转介给神经精神科医生，以确定其认知和神经行为状态。专家对测试结果不知情。
在研究的99名参与者中，39例健康，8例患有轻度阿尔茨海默病，38例患有遗忘型轻度认知障碍，5例患有继发性痴呆，9例患有混合性血管性痴呆和阿尔茨海默病。对于区分健康组与其他人群，FAST、AMTS,、MMSE和NBCSS问卷的ROC曲线下面积分别为0.692、0.629、0.734和0.751。
MMSE和NBCSS测试在区分健康组与其他人群方面比其他两项测试具有更好的诊断能力。
