具有不一致受体状态的同步双侧乳腺癌：治疗一名患者，应对两种疾病。
Synchronous Bilateral Breast Cancer With Discordant Receptor Status: Treating One Patient but Two Diseases.
作者信息
Ojo Ademola S, Shittu Adedoyin, Amadife Stacy, Jackson Devon, Grantham Mica, Ali Ahmed, Sarma Ravi
机构信息
Department of Internal Medicine, Howard University Hospital, Washington, DC, USA.
Department of Pathology, Howard University Hospital, Washington, DC, USA.
出版信息
World J Oncol. 2023 Jun;14(3):224-229. doi: 10.14740/wjon1603. Epub 2023 Jun 11.
The expression of hormone receptors (estrogen and progesterone) and human epidermal growth factor receptor-2 (HER2) has been used for both therapeutic and prognostic purposes in the management of breast cancer. The presence of a discordant receptor status complicates the approach to treatment in patients with synchronous bilateral breast cancer. We describe the case of a 45-year-old female with synchronous bilateral breast cancer with a triple-negative tumor and a contralateral HER2-positive tumor and discussed the impact of this on the approach to therapeutic management.
激素受体（雌激素和孕激素）以及人表皮生长因子受体2（HER2）的表达已用于乳腺癌治疗和预后评估。受体状态不一致使同步双侧乳腺癌患者的治疗方法变得复杂。我们描述了一例45岁同步双侧乳腺癌女性病例，一侧为三阴性肿瘤，对侧为HER2阳性肿瘤，并讨论了这对治疗管理方法的影响。
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