School of Nursing and Midwifery, University of Newcastle, New South Wales, Australia.
School of Nursing and Midwifery, University of Newcastle, New South Wales, Australia; School of Nursing, The University of Wollongong, New South Wales, Australia; World Health Organization Collaborating Centre for Nursing, Midwifery & Health Development, University of Technology Sydney, New South Wales, Australia.
Infect Dis Health. 2023 Aug;28(3):239-245. doi: 10.1016/j.idh.2023.05.006. Epub 2023 Jun 22.
Adults living in Residential Aged Care Facilities (RACFs) are highly susceptible to seasonal respiratory infections. Evidence indicates that the aerosols contaminated with virus particles in closed indoor spaces may play a significant role in the transmission of respiratory infections. In this protocol paper, we outline details of a planned RCT which aims to evaluate the effectiveness of portable in room air purifiers in reducing the risk of ARIs among residents in Australian RACFs. This study uses a multi-centre double-blind randomised crossover design. Three RACFs in a regional area of New South Wales will be invited to participate in the study. Air purifiers with or without high-efficiency particulate absorbing (HEPA) filters will be placed in the rooms of residents who are enrolled in the trial. The primary outcome will be a reduction in the incidence of ARI and the secondary outcomes will be the time to first infection, number of emergency department admissions, hospital admissions, and medical consultations due to an ARI.
To our knowledge, this will be the first RCT using air purifiers in resident rooms to identify their effect in reducing ARIs in RACFs. If our findings indicate some potential benefit for in-room air purification, it will help provide support and justification for larger trials, which may include a facility wide approach to air purification.
居住在养老院的成年人极易受到季节性呼吸道感染的影响。有证据表明,在封闭的室内空间中,被病毒颗粒污染的气溶胶可能在呼吸道感染的传播中起重要作用。在本研究方案中,我们概述了一项计划中的 RCT 的详细信息,该 RCT 旨在评估便携式室内空气净化器在降低澳大利亚养老院居民呼吸道感染风险方面的有效性。本研究采用多中心双盲随机交叉设计。新南威尔士州一个地区的三个养老院将被邀请参与这项研究。在参与试验的居民的房间内放置装有或不装有高效微粒空气过滤器的空气净化器。主要结果将是呼吸道感染发病率的降低,次要结果将是首次感染的时间、因呼吸道感染而急诊入院的次数、住院次数和因呼吸道感染而就诊的次数。
据我们所知,这将是首个使用室内空气净化器来确定其在降低养老院呼吸道感染方面效果的 RCT。如果我们的研究结果表明室内空气净化有一定的潜在益处,它将有助于为更大规模的试验提供支持和理由,这些试验可能包括对整个设施进行空气净化的方法。