奈凯花精油的化学成分及抗炎活性。
Chemical composition and anti-inflammatory activity of flower essential oil from Nakai.
机构信息
Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement/Guangxi Engineering Research Center of TCM Resource Intelligent Creation, National Center for TCM Inheritance and Innovation, Guangxi Botanical Garden of Medicinal Plants, Nanning, China.
National Engineering Research Center of Southwest Endangered Medicinal Resources Development, Guangxi Botanical Garden of Medicinal Plants, Nanning, China.
出版信息
Nat Prod Res. 2024 Sep;38(18):3207-3213. doi: 10.1080/14786419.2023.2223748. Epub 2023 Jun 24.
Nakai is an ornamental plant widely cultivated in East Asia. The essential oil of flowers (FEO) was extracted by hydrodistillation process and the volatile components were determined with gas chromatography coupled with mass spectrometry. The anti-inflammatory activity of FEO was investigated by using TPA-induced mouse ear inflammation model. The major components of FEO were identified as -tetracosane (29.85%), -heneicosane (17.45%), myristic acid (8.46%) and palmitaldehyde (6.22%). The TPA-induced mouse ear edema, water content, dermis thickness, epidermis thickness and nitric oxide production were decreased by FEO. Our findings suppose that the flower essential oil of exerted anti-inflammatory activity, and may be used in the development of anti-inflammatory products in future.
Nakai 是一种在东亚广泛种植的观赏植物。通过水蒸馏法从花朵中提取精油（FEO），并用气相色谱-质谱联用技术确定挥发性成分。使用 TPA 诱导的小鼠耳炎模型研究了 FEO 的抗炎活性。FEO 的主要成分鉴定为 -二十四烷（29.85%）、-正二十一烷（17.45%）、肉豆蔻酸（8.46%）和棕榈醛（6.22%）。FEO 降低了 TPA 诱导的小鼠耳肿胀、含水量、真皮厚度、表皮厚度和一氧化氮的产生。我们的研究结果表明，当归花精油具有抗炎活性，将来可能用于开发抗炎产品。
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