Medical University of South Carolina, Department of Otolaryngology-Head & Neck Surgery, 135 Rutledge Avenue, Charleston, South Carolina 29425, USA.
University of Michigan, Kresge Hearing Research Institute, Department of Otolaryngology- Head & Neck Surgery, 4605 Medical Science Unit II, Ann Arbor, Michigan 48109,
JASA Express Lett. 2023 Jun 1;3(6). doi: 10.1121/10.0019806.
The electrically evoked compound action potentials (ECAPs) amplitude-growth function (AGF) slope correlates with spiral ganglion neuron (SGN) density in the cochlear implanted cochlea. Electrode insertion angle and medial-lateral distance covary from base to apex; in some human ears, SGN survival varies from base to apex, making it difficult to parse out contributing factors to the ECAP AGF slope. Evoked compound action potentials were analyzed on each electrode and compared to post-operative computerized tomography scans. When controlling for medial-lateral distance, insertion angle does not influence ECAP AGF slope.
电诱发复合动作电位（ECAP）幅度增长函数（AGF）斜率与植入耳蜗中的螺旋神经节神经元（SGN）密度相关。电极插入角度和内外侧距离从基底到顶点变化；在一些人类耳朵中，SGN 存活从基底到顶点变化，这使得难以解析影响 ECAP AGF 斜率的因素。在每个电极上分析诱发复合动作电位，并与术后计算机断层扫描进行比较。当控制内外侧距离时，插入角度不会影响 ECAP AGF 斜率。
