经济困难在晚期癌症患者躯体症状与抑郁间的中介作用

The Role of Financial Difficulties as a Mediator between Physical Symptoms and Depression in Advanced Cancer Patients.

机构信息

Faculty of Psychology, University of Barcelona, 08007 Barcelona, Spain.

Department of Medical Oncology, Hospital Universitario Central de Asturias, Instituto de Investigación del Principado de Asturias, ISPA, 33011 Oviedo, Spain.

出版信息

Curr Oncol. 2023 Jun 12;30(6):5719-5726. doi: 10.3390/curroncol30060429.

Abstract

Financial difficulties experienced by cancer patients negatively impact the mental health of the patients. The objective of this study was to examine the mediating role of financial difficulties between physical symptoms and depression in patients with advanced cancer. A prospective, cross-sectional design was adopted in the study. The data were collected from 861 participants with advanced cancer in 15 different tertiary hospitals in Spain. The participants' socio-demographic characteristics were collected using a standardized self-report form. Hierarchical linear regression models were used to explore the mediating role of financial difficulties. In the results, 24% of patients reported a high level of financial difficulties. Physical symptoms were positively associated with financial difficulties and depression (β = 0.46 and β = 0.43, respectively), and financial difficulties was positively associated with depression (β = 0.26). Additionally, financial difficulties played a role in explaining the relationship between physical symptoms and depression, showing a standardized regression coefficient of 0.43 which decreased to 0.39 after the financial difficulties were controlled. Healthcare professionals should consider the importance of providing financial resources and emotional support to help patients and their families cope with the financial burden associated with cancer treatment and its symptoms.

摘要

癌症患者面临的经济困难会对其心理健康产生负面影响。本研究旨在探讨经济困难在晚期癌症患者身体症状和抑郁之间的中介作用。研究采用前瞻性、横断面设计。数据来自西班牙 15 家不同三级医院的 861 名晚期癌症患者。采用标准化自我报告表收集参与者的社会人口统计学特征。采用分层线性回归模型探讨经济困难的中介作用。结果显示,24%的患者报告存在较高水平的经济困难。身体症状与经济困难和抑郁呈正相关(β=0.46 和 β=0.43),经济困难与抑郁呈正相关(β=0.26)。此外,经济困难在解释身体症状和抑郁之间的关系中起作用,标准化回归系数为 0.43,在控制经济困难后降至 0.39。医疗保健专业人员应考虑提供财务资源和情感支持的重要性,以帮助患者及其家属应对与癌症治疗及其症状相关的经济负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d020/10297664/dcb01ebaaa40/curroncol-30-00429-g001.jpg

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