Lafaie Ludovic, Chanelière-Sauvant Anne-Françoise, Magné Nicolas, Bouleftour Wafa, Tinquaut Fabien, Célarier Thomas, Bertoletti Laurent
Département de Gérontologie Clinique, CHU de Saint-Étienne, F-42055 Saint-Etienne, France.
INSERM, UMR1059, Equipe Dysfonction Vasculaire et Hémostase, Université Jean-Monnet, F-42055 Saint-Etienne, France.
Geriatrics (Basel). 2023 Jun 1;8(3):62. doi: 10.3390/geriatrics8030062.
The management (diagnostic and therapeutic) of cancer in the geriatric population involves a number of complex difficulties. The aim of this study was to assess the impact of a medical specialty on the diagnostic and therapeutic management of elderly cancer patients. Four clinical scenarios of cancer in the geriatric population, with a dedicated survey to gather information regarding each clinical case's diagnostic and therapeutic approaches, as well as the different criteria influencing physicians' therapeutic decisions, were exposed to geriatricians, oncologists, and radiotherapists in Saint-Etienne. The surveys were filled out by 13 geriatricians, 11 oncologists, and 7 radiotherapists. There was a homogeneity of responses regarding the confirmation of cancer diagnostics in the elderly. There were strong disparities (inter- and intra-specialties) for several clinical situations regarding the therapeutic management of cancer. There were significant disparities in terms of surgical management, the implementation of a chemotherapy protocol, and the adaptation of the chemotherapy dosage. Contrary to oncologists, who primarily consider the G8 and the Karnofsky score, geriatric autonomy scores and frailty with cognitive assessment were the key factors determining diagnostic/therapeutic therapy for geriatricians. These results raise important ethical questions, requiring specific studies in geriatric populations to provide the homogenous management of elderly patients with cancer.
老年人群癌症的管理(诊断和治疗)存在诸多复杂难题。本研究旨在评估医学专科对老年癌症患者诊断和治疗管理的影响。向圣艾蒂安的老年病科医生、肿瘤学家和放射肿瘤学家展示了老年人群癌症的四种临床场景,并通过专门调查收集有关每个临床病例诊断和治疗方法以及影响医生治疗决策的不同标准的信息。13名老年病科医生、11名肿瘤学家和7名放射肿瘤学家填写了调查问卷。在老年癌症诊断的确证方面,回答具有同质性。在癌症治疗管理的几种临床情况中,(不同专科之间和专科内部)存在很大差异。在手术管理、化疗方案的实施以及化疗剂量的调整方面存在显著差异。与主要考虑G8和卡诺夫斯基评分的肿瘤学家不同,老年自主评分和伴有认知评估的衰弱是老年病科医生决定诊断/治疗的关键因素。这些结果引发了重要的伦理问题,需要针对老年人群进行具体研究,以实现老年癌症患者的同质化管理。