Bettio Valentina, Mazzucco Eleonora, Aleni Chiara, Cracas Silvia, Rinaldi Carmela, Antona Annamaria, Varalda Marco, Venetucci Jacopo, Ferrante Daniela, Rimedio Antonio, Capello Daniela
UPO Biobank, University of Piemonte Orientale, 28100 Novara, Italy.
Department of Translational Medicine, Center of Excellence in Aging Sciences, University of Piemonte Orientale, 28100 Novara, Italy.
J Pers Med. 2023 May 29;13(6):911. doi: 10.3390/jpm13060911.
Biobanks are driving motors of precision and personalized medicine by providing high-quality biological material/data through the standardization and harmonization of their collection, preservation, and distribution. UPO Biobank was established in 2020 as an institutional, disease, and population biobank within the University of Piemonte Orientale (UPO) for the promotion and support of high-quality, multidisciplinary studies. UPO Biobank collaborates with UPO researchers, sustaining academic translational research, and supports the Novara Cohort Study, a longitudinal cohort study involving the population in the Novara area that will collect data and biological specimens that will be available for epidemiological, public health, and biological studies on aging. UPO Biobank has been developed by implementing the quality standards for the field and the ethical and legal issues and normative about privacy protection, data collection, and sharing. As a member of the "Biobanking and Biomolecular Resources Research Infrastructure" (BBMRI) network, UPO Biobank aims to expand its activity worldwide and launch cooperation with new national and international partners and researchers. The objective of this manuscript is to report an institutional and operational experience through the description of the technical and procedural solutions and ethical and scientific implications associated with the establishment of this university research biobank.
生物样本库通过对样本采集、保存和分发进行标准化和协调,提供高质量的生物材料/数据,从而推动精准医学和个性化医疗的发展。东方皮埃蒙特大学(UPO)生物样本库成立于2020年,是一所机构性、疾病和人群生物样本库,旨在促进和支持高质量的多学科研究。UPO生物样本库与UPO的研究人员合作,支持学术转化研究,并支持诺瓦拉队列研究,这是一项涉及诺瓦拉地区人群的纵向队列研究,将收集可用于衰老流行病学、公共卫生和生物学研究的数据和生物标本。UPO生物样本库通过实施该领域的质量标准以及隐私保护、数据收集和共享方面的伦理和法律问题及规范而得以发展。作为“生物样本库和生物分子资源研究基础设施(BBMRI)”网络的成员,UPO生物样本库旨在将其活动扩展到全球,并与新的国内和国际合作伙伴及研究人员开展合作。本文的目的是通过描述与建立这个大学研究生物样本库相关的技术和程序解决方案以及伦理和科学影响,来报告一项机构和运营经验。