嗜酸细胞性食管炎治疗的新进展。
Recent Advances in the Treatment of Eosinophilic Esophagitis.
机构信息
Division of Gastroenterology, Hepatology and Nutrition, University of Utah School of Medicine, Salt Lake City, Utah.
Food Allergy Center and Division of Pediatric Allergy and Immunology, and Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, Mass.
出版信息
J Allergy Clin Immunol Pract. 2023 Sep;11(9):2654-2663. doi: 10.1016/j.jaip.2023.06.035. Epub 2023 Jun 28.
Abstract
Eosinophilic esophagitis is an increasingly common inflammatory allergic disease of the esophagus characterized by esophageal eosinophilia and symptoms of esophageal dysfunction. The therapeutic landscape has rapidly evolved for this emerging type 2 inflammatory disorder. We review traditional therapies including updates and expert opinions in addition to promising therapies on the horizon and the history of therapies that failed to meet end points and highlight knowledge gaps for future investigations.
摘要
嗜酸性粒细胞性食管炎是一种日益常见的食管炎症性过敏性疾病，其特征是食管嗜酸性粒细胞增多和食管功能障碍症状。对于这种新兴的 2 型炎症性疾病，治疗领域已经迅速发展。我们回顾了传统疗法，包括更新和专家意见，以及有前途的治疗方法，并探讨了未能达到终点的治疗方法的历史，突出了未来研究的知识空白。
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