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- 伴米粒体形成的关节炎:病例报告及文献综述

-Caused Arthritis with Rice Body Formation: A Case Presentation and Literature Review.

作者信息

Qi Weihui, Ren Yanyun, Wang Huang, Wan Yue, Pan Hao, Yao Jun

机构信息

Department of Orthopaedics, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, People's Republic of China.

Department of Orthopaedics, Hangzhou Ding Qiao Hospital, Hangzhou, People's Republic of China.

出版信息

Infect Drug Resist. 2023 Jun 26;16:4123-4135. doi: 10.2147/IDR.S416990. eCollection 2023.

Abstract

A 68-year-old male patient came to the orthopedics department because of swelling and pain in his left shoulder joint. He received more than 15 intraarticular steroid injections in the shoulder joint at a local private hospital. MRI showed that the synovial membrane of the joint capsule was thickened and swollen, and there were extensive "rice body-like" low T2 signal shadows filling. Arthroscopic removal of rice bodies and subtotal bursectomy were performed. The observation channel was placed through the posterior approach, and a large amount of rice bodies in yellow bursa fluid were observed to flow out. Rice bodies with a diameter of approximately 1-5 mm filled the joint cavity were seen in the observation channel. The histopathological examination of the rice body showed that it was mainly composed of fibrin without a clear tissue structure. Bacterial and fungal cultures of synovial fluid suggested infection, so the patient received antifungal treatment. However, the shoulder swelled again after three weeks, MRI revealed that there was significant fluid accumulation in the subacromial-subdeltoid region with necrotic synovial tissue floating and ultrasound examination showed joint cavity effusion, synovial hyperplasia, and some synovium looked like "floating weeds". After 2 weeks, there were recurrent rice bodies in the articular cavity. Arthroscopic surgery was performed again to clean the joint and a catheter was placed for irrigation and drainage, and a large amount of necrotic synovial tissue floating as seen in ultrasound. Finally, patient received sensitive antifungal treatment and did not relapse within 6 months. During the recurrence in the current case, we recorded the process of rice body formation, which has for the first time been reported.

摘要

一名68岁男性患者因左肩肿胀疼痛前来骨科就诊。他在当地一家私立医院接受了15次以上的肩关节腔内类固醇注射。MRI显示关节囊滑膜增厚肿胀,有广泛的“米粒体样”低T2信号影充填。行关节镜下米粒体清除及滑囊次全切除术。观察通道经后路置入,可见大量黄色滑囊液中的米粒体流出。观察通道内可见直径约1-5mm的米粒体充满关节腔。米粒体的组织病理学检查显示其主要由纤维蛋白组成,无明确组织结构。滑液细菌和真菌培养提示感染,因此患者接受了抗真菌治疗。然而,三周后肩部再次肿胀,MRI显示肩峰下-三角肌下区域有大量积液,坏死的滑膜组织漂浮,超声检查显示关节腔积液、滑膜增生,部分滑膜呈“漂浮的水草”样。2周后,关节腔内又出现了复发性米粒体。再次行关节镜手术清理关节并置入导管进行冲洗引流,超声可见大量坏死的滑膜组织漂浮。最后,患者接受了敏感的抗真菌治疗,6个月内未复发。在本例复发过程中,我们记录了米粒体形成过程,这是首次报道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1761/10312336/91834d800462/IDR-16-4123-g0001.jpg

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