Ahmad NurFarrahain Nadia, Ghazali Nik Nazri Nik, Abdul Rani Ahmad Taufiq, Othman Mohammad Hafiz, Kee Chia Ching, Jiwanti Prastika Krisma, Rodríguez-Gómez Arturo, Wong Yew Hoong
Department of Mechanical Engineering, Faculty of Engineering, Universiti Malaya, Kuala Lumpur 50603, Federal Territory, Malaysia.
School of Mechanical Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, Johor Bahru 81310, Johor, Malaysia.
Micromachines (Basel). 2023 Apr 19;14(4):881. doi: 10.3390/mi14040881.
This paper presents a finger-actuated micropump with a consistent flow rate and no backflow. The fluid dynamics in interstitial fluid (ISF) extraction microfluidics are studied through analytical, simulation, and experimental methods. Head losses, pressure drop, diodocity, hydrogel swelling, criteria for hydrogel absorption, and consistency flow rate are examined in order to access microfluidic performance. In terms of consistency, the experimental result revealed that after 20 s of duty cycles with full deformation on the flexible diaphragm, the output pressure became uniform and the flow rate remained at nearly constant levels of 2.2 μL/min. The flow rate discrepancy between the experimental and predicted flow rates is around 22%. In terms of diodicity, when the serpentine microchannel and hydrogel-assisted reservoir are added to the microfluidic system integration, the diodicity increases by 2% (Di = 1.48) and 34% (Di = 1.96), respectively, compared to when the Tesla integration (Di = 1.45) is used alone. A visual and experimentally weighted analysis finds no signs of backflow. These significant flow characteristics demonstrate their potential usage in many low-cost and portable microfluidic applications.
本文介绍了一种具有恒定流速且无回流的手指驱动微泵。通过分析、模拟和实验方法研究了组织间液(ISF)提取微流体中的流体动力学。研究了水头损失、压降、二极管特性、水凝胶溶胀、水凝胶吸收标准和恒定流速,以评估微流体性能。在一致性方面,实验结果表明,在柔性隔膜完全变形的20秒占空比后,输出压力变得均匀,流速保持在近2.2μL/min的恒定水平。实验流速与预测流速之间的差异约为22%。在二极管特性方面,与单独使用特斯拉集成(Di = 1.45)相比,当在微流体系统集成中添加蛇形微通道和水凝胶辅助储液器时,二极管特性分别增加了2%(Di = 1.48)和34%(Di = 1.96)。视觉和实验加权分析未发现回流迹象。这些显著的流动特性证明了它们在许多低成本和便携式微流体应用中的潜在用途。