From the State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou, China (J. Zhang, Han, Chen, Z. Liu, Y. Zhang, Qiu, Tan, Luo, Y. Liu); Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China (J. Zhang, Han, Chen, Z. Liu, Y. Zhang, Qiu, Tan, Luo, Y. Liu).
J Cataract Refract Surg. 2023 Sep 1;49(9):956-963. doi: 10.1097/j.jcrs.0000000000001253.
To determine the optimal intraocular lens (IOL) calculation formula for vitrectomized eyes with diverse surgical and biometric characteristics.
Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Retrospective consecutive case series study.
This study included 974 vitrectomized eyes (974 patients) scheduled for phacoemulsification with IOL implantation. 11 formulas were evaluated: Barrett Universal II (BUII), Emmetropia Verifying Optical, Hoffer-QST, Kane, Ladas Super Formula, Pearl-DGS, Radial Basis Function (RBF), Haigis, HofferQ, Holladay1, and SRK/T. Risk factors for prediction error (PE) exceeding 1 diopter (D) were determined using multiple logistic regression. Subgroup analyses were performed based on surgical history and biometric parameters.
The risk of hyperopic PE (>1 D) was higher in patients with silicone oil tamponade (odds ratio [OR], 1.82) and longer axial length (AL) (OR, 1.55), while patients with previous scleral buckling (OR, 2.43) or ciliary sulcus IOL implantation (OR, 6.65) were more susceptible to myopic PE (<-1 D). The Kane formula had the highest overall prediction accuracy, and also the best in silicone oil-filled eyes and the flat cornea subgroup. The BUII and RBF displayed the optimal performance in eyes with previous scleral buckle and steep cornea, respectively. In eyes with an AL ≥ 26 mm, the Holladay1 with the nonlinear version of the Wang-Koch AL adjustment (Holladay1-WKn) showed the lowest absolute PE and highest percentage within ± 1.0 D of PE.
The Kane achieved the highest overall prediction accuracy in vitrectomized eyes. The optimal formula for eyes with previous scleral buckle, steep cornea, or long AL was BUII, RBF, and Holladay1-WKn, respectively.
确定不同手术和生物测量特征的玻璃体切割眼中最佳的人工晶状体（IOL）计算公式。
中山大学中山眼科中心，广州，中国。
回顾性连续病例系列研究。
本研究纳入了 974 只接受白内障超声乳化吸除术联合 IOL 植入术的玻璃体切割眼（974 例患者）。评估了 11 种公式：Barrett Universal II（BUII）、Emmetropia Verifying Optical、Hoffer-QST、Kane、Ladas Super Formula、Pearl-DGS、Radial Basis Function（RBF）、Haigis、HofferQ、Holladay1 和 SRK/T。使用多因素逻辑回归确定预测误差（PE）超过 1 屈光度（D）的风险因素。根据手术史和生物测量参数进行亚组分析。
硅油填充（比值比 [OR]，1.82）和较长眼轴（AL）（OR，1.55）的患者发生远视性 PE（>1 D）的风险更高，而有巩膜扣带术（OR，2.43）或睫状沟 IOL 植入术（OR，6.65）史的患者则更容易发生近视性 PE（<-1 D）。Kane 公式的总体预测准确性最高，在硅油填充眼中和扁平角膜亚组中表现最佳。BUII 和 RBF 在有巩膜扣带术史和陡峭角膜的眼中表现最佳。在 AL≥26 mm 的眼中，Wang-Koch AL 调整的非线性版本 Holladay1（Holladay1-WKn）的绝对 PE 最低，PE 在±1.0 D 范围内的百分比最高。
Kane 公式在玻璃体切割眼中的总体预测准确性最高。对于有巩膜扣带术史、陡峭角膜或长 AL 的眼，最佳公式分别为 BUII、RBF 和 Holladay1-WKn。
