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妊娠期非酒精性脂肪性肝病

Non-alcoholic fatty liver disease in pregnancy.

作者信息

Benson Charlotte S, Cobbold Jeremy F, Frise Charlotte J

机构信息

Department of Obstetrics, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Slough, UK.

Oxford Liver Unit and NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

出版信息

Obstet Med. 2023 Jun;16(2):116-119. doi: 10.1177/1753495X211034709. Epub 2021 Aug 27.

Abstract

Non-alcoholic fatty liver disease (NAFLD) is now the commonest liver pathology in the UK; however, relatively little is known about its course in pregnancy or the effect it has on maternal or fetal outcomes. Described here is a 24-year-old woman in her first pregnancy who presented with non-specific symptoms and raised alanine aminotransferase with ultrasonography of her liver showing changes of steatosis and suspicious for cirrhosis, leading to a diagnosis of NAFLD. The case illustrates the need for the clinician to have awareness of this increasingly prevalent condition and for multidisciplinary management.

摘要

非酒精性脂肪性肝病(NAFLD)现已成为英国最常见的肝脏疾病;然而,对于其在妊娠期间的病程以及对母婴结局的影响,我们了解得相对较少。本文描述了一名24岁的初孕妇,她出现非特异性症状,丙氨酸转氨酶升高,肝脏超声检查显示有脂肪变性改变且怀疑有肝硬化,最终诊断为NAFLD。该病例表明临床医生需要认识到这种日益普遍的疾病,并进行多学科管理。

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