Pelayo Mar, Sancho-Sauco Javier, Sanchez-Zurdo Javier, Abarca-Martinez Leopoldo, Borrero-Gonzalez Carlota, Sainz-Bueno Jose Antonio, Alcazar Juan Luis, Pelayo-Delgado Irene
HM Puerta del Sur, HM Rivas Hospital, 3428521 Madrid, Spain.
Department of Obstetrics and Gynecology, Universitary Hospital Ramón y Cajal, Alcalá de Henares University, 3428034 Madrid, Spain.
Diagnostics (Basel). 2023 Jun 23;13(13):2152. doi: 10.3390/diagnostics13132152.
Several ultrasound (US) features help ultrasound experts in the classification of benign vs. malignant adnexal masses. US scores serve in this differentiation, but they all have misdiagnoses. The main objective of this study is to evaluate what ultrasound characteristics are associated with malignancy influencing ultrasound scores.
This is a retrospective analysis of ultrasound features of adnexal lesions of women managed surgically. Ultrasound characteristics were analyzed, and masses were classified by subjective assessment of the ultrasonographer (SA) and other ultrasound scores (IOTA Simple Rules Risk Assessment SRRA, ADNEX model, and O-RADS).
Of a total of 187 adnexal masses studied, 134 were benign (71.7%) and 53 were malignant (28.3%). SA, IOTA SRRA, ADNEX model with or without CA125 and O-RADS had high levels of sensitivity (93.9%, 81.1%, 94.3%, 88.7%, 98.1%) but lower specificity (80.2%, 82.1%, 82.8%, 77.6%, 73.1%) with similar AUC (0.87, 0.87, 0.92, 0.90, 0.86). Ultrasound features significantly related with malignancy were the presence of irregular contour, absence of acoustic shadowing, vascularized solid areas, ≥1 papillae, vascularized septum, and moderate-severe ascites.
IOTA SRRA, ADNEX model, and O-RADS can help in the classification of benign and malignant masses. Certain ultrasound characteristics studied in ultrasound scores are associated with malignancy.
多种超声（US）特征有助于超声专家对附件区良恶性肿块进行分类。超声评分在这种鉴别中发挥作用，但它们都存在误诊情况。本研究的主要目的是评估哪些超声特征与影响超声评分的恶性肿瘤相关。
这是一项对接受手术治疗的女性附件区病变超声特征的回顾性分析。分析了超声特征，并通过超声检查者的主观评估（SA）和其他超声评分（IOTA简单规则风险评估SRRA、ADNEX模型和O-RADS）对肿块进行分类。
在总共研究的187个附件区肿块中，134个为良性（71.7%），53个为恶性（28.3%）。SA、IOTA SRRA、含或不含CA125的ADNEX模型以及O-RADS具有较高的敏感性（93.9%、81.1%、94.3%、88.7%、98.1%），但特异性较低（80.2%、82.1%、82.8%、77.6%、73.1%），AUC相似（0.87、0.87、0.92、0.90、0.86）。与恶性肿瘤显著相关的超声特征包括轮廓不规则、无声影、实性区域有血管、≥1个乳头、血管化隔膜以及中重度腹水。
IOTA SRRA、ADNEX模型和O-RADS有助于对良恶性肿块进行分类。超声评分中研究的某些超声特征与恶性肿瘤相关。
